2013
DOI: 10.1039/c2tb00179a
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A pH sensitive ratiometric fluorophore and its application for monitoring the intracellular and extracellular pHs simultaneously

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Cited by 81 publications
(67 citation statements)
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“…Halo-fluorochromic properties of molecules often depend on ionization of a specific location on the molecule resulting in fluorescence shifts [40]. The pKa of this ionization process often shifts greatly depending on the solvent environment of the molecule [41].…”
Section: Discussionmentioning
confidence: 99%
“…Halo-fluorochromic properties of molecules often depend on ionization of a specific location on the molecule resulting in fluorescence shifts [40]. The pKa of this ionization process often shifts greatly depending on the solvent environment of the molecule [41].…”
Section: Discussionmentioning
confidence: 99%
“…The shift in the emission can overcome the disturbances induced by environmental fluorescence to improve the selectivity and sensitivity. [28][29][30][31][32][33][34][35] Although a variety of fluorescent ratiometric sensors for Cu 2+ , Fe 3+ , etc. have been documented, [36][37][38][39][40][41][42] only a few ratiometric Hg 2+ probes have been reported to date.…”
Section: Introductionmentioning
confidence: 99%
“…So far, a number of excellent pH probes working for weak acidic organelles (such as lysosomes, pH 4.5-5.0) [7][8][9][10][11][12][13][14][15][16][17] or near neutral cytosol (pH 6. 8-7.4) [7,[18][19][20][21][22][23] have been exploited, and some are commercially available [7]. Unfortunately, relatively less attention is paid on the fluorescent pH probes functioning over extremely acidic range (pH < 4).…”
Section: Introductionmentioning
confidence: 97%