A photoinduced multicomponent intramolecular cyclization/hydroxytrifluoromethylation cascade: facile access to polyfunctionalized 3,4-dihydroquinazolinones
Changjun Zhang,
Yuxin Ding,
Wenkai Huang
et al.
Abstract:Multicomponent reactions (MCRs) have demonstrated enormous potential in direct, single-step synthesis of structural diversity of chemical entities. However, the exploration of the photochemical MCRs approach for the construction of N-heterocyclics,...
A 100% atom economical construction of hydroxyalkylated N-heteroarenes through decatungstate-catalyzed tandem cyclization/self-hydrogenation of isocyanides and aldehydes under exogenous hydrogen reagent- and byproduct-free conditions was developed.
A 100% atom economical construction of hydroxyalkylated N-heteroarenes through decatungstate-catalyzed tandem cyclization/self-hydrogenation of isocyanides and aldehydes under exogenous hydrogen reagent- and byproduct-free conditions was developed.
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