A Pilot Study of a Mobile Intervention to Support Mental Health and Adherence Among Adolescents Living with HIV in Western Kenya

Chory, Ashley; Callen, Grant; Nyandiko, Winstone; Njoroge, Tabitha; Ashimosi, Celestine; Aluoch, Josephine; Scanlon, Michael; McAteer, Carole I.; Apondi, Edith; Vreeman, Rachel C.

doi:10.1007/s10461-021-03376-9

Cited by 41 publications

(69 citation statements)

References 67 publications

(75 reference statements)

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“…The majority of articled revised were studies conducted in the United States (12) [ 77 , 80 – 82 , 84 , 88 , 90 , 94 , 95 , 99 , 100 , 104 ], three were from Kenya [ 86 , 92 , 102 ] and three from South Africa [ 85 , 93 , 101 ]. Locations like China, the United Kingdom and Zambia had two studies included in this review [ 79 , 87 , 91 , 96 , 98 , 103 ] and, from the total of articles included, only one article was from Malaysia, Nigeria, Tanzania and Uganda [ 78 , 83 , 89 , 97 ].…”

Section: Resultsmentioning

confidence: 99%

“…Regarding the study type, eight of the included articles corresponded to pilot studies [ 77 , 79 , 86 , 88 , 92 , 101 , 102 , 104 ], while seven articles explicitly indicate a clinical trial type of design [ 83 , 85 , 86 , 90 , 95 , 96 , 98 ], as well as five protocols [ 80 – 82 , 93 , 94 ] and five qualitative studies [ 87 , 91 , 99 , 100 , 103 ]. Only two Randomized Controlled Trials [ 78 , 97 ], and one cohort study [ 89 ].…”

Section: Resultsmentioning

confidence: 99%

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Internet-based peer support interventions for people living with HIV: A scoping review

et al. 2022

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Peer support interventions for people living with HIV and AIDS (PLWHA) are effective, but their associated time and material costs for the recipient and the health system make them reachable for only a small proportion of PLWHA. Internet-based interventions are an effective alternative for delivering psychosocial interventions for PLWHA as they are more accessible. Currently, no reviews are focusing on internet-based interventions with peer support components. This scoping review aims to map the existing literature on psychosocial interventions for PLWHA based on peer support and delivered through the internet. We conducted a systematic scoping review of academic literature following methodological guidelines for scoping reviews, and 28 articles met our criteria. We summarized the main characteristics of the digital peer support interventions for PLWHA and how they implemented peer support in a virtual environment. Overall the reported outcomes appeared promising, but more robust evidence is needed.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Internet-based peer support interventions for people living with HIV: A scoping review

et al. 2022

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“…Limited data are available regarding the prevalence of mental health disorders among ALHIV in African countries [22]. A recent pilot study in this population reported depression 3.3% and anxiety 6.7% on baseline assessments [47]. Larger studies among ALHIV in Kenya and other countries in the region have found higher rates of depression (17.8%-25%) and anxiety (32.3%) [50][51][52][53].…”

Section: Plos Onementioning

confidence: 86%

“…Overall proportions of taking a dose >1 hour late in the last 7 days, missing at least 1 dose in the past 7 days, and forgetting to take ART within the last 3 days were 19.5%, 6.3%, and 6.3%, respectively. Studies of adolescent-or caregiver-reported adolescent adherence to ART in this setting have previously noted slightly higher proportions of taking ART >1 hour late in the last 7 days (26-29%); missing at least 1 dose in the past 7 days (16-18%); and forgetting to take ART within the last 3 days (8%) [47][48][49]. It is possible that respondents were less likely to report adherence challenges in phone surveys than in inperson studies.…”

Section: Plos Onementioning

confidence: 96%

Social, economic, and health effects of the COVID-19 pandemic on adolescents retained in or recently disengaged from HIV care in Kenya

et al. 2021

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Introduction Adolescents living with HIV (ALHIV, ages 10–19) experience complex challenges to adhere to antiretroviral therapy (ART) and remain in care, and may be vulnerable to wide-scale disruptions during the COVID-19 pandemic. We assessed for a range of effects of the pandemic on ALHIV in western Kenya, and whether effects were greater for ALHIV with recent histories of being lost to program (LTP). Methods ALHIV were recruited from an ongoing prospective study at 3 sites in western Kenya. The parent study enrolled participants from February 2019–September 2020, into groups of ALHIV either 1) retained in care or 2) LTP and traced in the community. Phone interviews from July 2020–January 2021 assessed effects of the pandemic on financial and food security, healthcare access and behaviors, and mental health. Responses were compared among the parent study groups. Results Phone surveys were completed with 334 ALHIV or their caregivers, including 275/308 (89.3%) in the retained group and 59/70 (84.3%) among those LTP at initial enrollment. During the pandemic, a greater proportion of LTP adolescents were no longer engaged in school (45.8% vs. 36.4%, p = 0.017). Over a third (120, 35.9%) of adolescents reported lost income for someone they relied on. In total, 135 (40.4%) did not have enough food either some (121, 36.2%) or most (14, 4.2%) of the time. More LTP adolescents (4/59, 6.8% vs. 2/275, 0.7%, p = 0.010) reported increased difficulties refilling ART. Adolescent PHQ-2 and GAD-2 scores were ≥3 for 5.6% and 5.2%, respectively. Conclusions The COVID-19 pandemic has had devastating socioeconomic effects for Kenyan ALHIV and their households. ALHIV with recent care disengagement may be especially vulnerable. Meanwhile, sustained ART access and adherence potentially signal resilience and strengths of ALHIV and their care programs. Findings from this survey indicate the critical need for support to ALHIV during this crisis.

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“…Nine studies targeted orphans and vulnerable adolescents from poor backgrounds ( 30 , 37 , 41 , 62 ), with one of the studies focusing on AIDS orphaned adolescents ( 30 ). Overall, four interventions were aimed at improving the mental health of HIV-affected adolescents ( 30 , 32 , 40 , 80 ). Ten of the community-based interventions were home-based and involved family meetings involving caregivers, parents, and adolescents.…”

Section: Resultsmentioning

confidence: 99%

Mental health interventions for adolescents in sub-Saharan Africa: A scoping review

Mabrouk

Mbithi²,

Chongwo³

et al. 2022

Front. Psychiatry

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BackgroundGlobally, adolescents are vulnerable to mental health problems, particularly those from sub-Saharan Africa (SSA) due to impoverished living conditions and a higher prevalence of chronic conditions such as HIV/AIDS in the region. The COVID-19 pandemic has further exacerbated this risk. This calls for an urgent need for evidence-based adolescent mental health interventions to reduce the risk and burden of mental health problems in SSA. The review aims to identify and characterize existing adolescent mental health interventions in SSA, as well as to evaluate their implementation strategies and effectiveness.MethodsWe systematically searched PubMed, African Index Medicus, PsycINFO, Web of Science, and CINAHL databases for relevant articles. Furthermore, we searched gray literature databases, including Think Tank search, open gray, NGO search engine, and IGO search engine for additional relevant articles. The scoping review was conducted to identify original research articles on mental health interventions among adolescents in sub-Saharan Africa published from database inception to 31 December 2021. We carried out a narrative synthesis to report our findings.ResultsOur literature search generated 4,750 studies, of which 1,141 were duplicates, 3,545 were excluded after screening, and 64 articles met the inclusion criteria. The 64 studies describe a total of 57 unique mental health interventions comprising 40,072 adolescents. The nature of these interventions was diverse, encompassing various implementation strategies such as economic-based, family strengthening, psychoeducation, interpersonal psychotherapy, Cognitive Behavioral Therapy, and resilience training, among others. Most of the interventions were selective interventions that targeted adolescents at high risk of developing mental health problems including adolescents living with HIV, war-affected adolescents, orphans, adolescents from poorer backgrounds, and survivors of sexual violence. Half of the interventions were delivered by lay persons. Sixty-two of the eligible studies examined the effectiveness of the mental health interventions, of which 55 of them reported a positive significant impact on various mental health outcomes.ConclusionsThe review findings show that there exist several diverse interventions that promote mental health among adolescents in sub-Saharan Africa. These interventions can be implemented in diverse settings including schools, communities, health facilities, and camps, and can be delivered by lay persons.

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A Pilot Study of a Mobile Intervention to Support Mental Health and Adherence Among Adolescents Living with HIV in Western Kenya

Cited by 41 publications

References 67 publications

Internet-based peer support interventions for people living with HIV: A scoping review

Internet-based peer support interventions for people living with HIV: A scoping review

Social, economic, and health effects of the COVID-19 pandemic on adolescents retained in or recently disengaged from HIV care in Kenya

Mental health interventions for adolescents in sub-Saharan Africa: A scoping review

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