A polygenic risk score for progressive non-alcoholic fatty liver disease risk stratification

Bianco, Cristiana; Pelusi, S.; Baselli, Guido; Zanoni, I. Holly; Alice, Taliento; Paola, Dimitri; Rametta, Raffaela; Borroni, V.; Alessandro, Federico; Gentilucci, Umberto Vespasiani; D’Ambrosio, Roberta; Bugianesi, Elisabetta; Salvatore, Veronica; Miele, Luca; Reeves, Helen L.; Soardo, G.; Pastori, Daniele; Valenti, L.

doi:10.1016/s0168-8278(20)30587-0

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Genetic Factors1

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Cited by 5 publications

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“…Recently, a multicentre European study combined PNPLA3, TM6SF2, GCKR, MBOAT7 and HSD17B13 to derive polygenic risk scores for HCC prediction in NAFLD patients and the general population. [17] Although most of these genetic markers have been explored in the Asian population, data on NAFLD-associated HCC are largely lacking. In addition, the prevalence and functional significance of the genetic markers may differ in the Asian population.…”

Section: Genetic Factorsmentioning

confidence: 99%

Asian perspective on NAFLD-associated HCC

Yip

Lee

Chan

et al. 2022

Journal of Hepatology

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Section: Genetic Factorsmentioning

confidence: 99%