A Population‐Based Survey on Gastrointestinal Tract Symptoms and <i>Helicobacter pylori</i> Infection in Children and Adolescents

Giacomo, Costantino De; Valdambrini, V.; Lizzoli, Francesca; Gissi, Anna; Palestra, Marina; Tinelli, Carmine; Zagari, M.; Bazzoli, Franco

doi:10.1046/j.1523-5378.2002.00109.x

Cited by 55 publications

(39 citation statements)

References 29 publications

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“…A large number of reports have been produced on H. pylori and showed that it is able to infect at least 50 % of the world's population (Perry et al 2006) especially in their early life (Sabbi et al 2008) and persists throughout the rest of their lifetime. According to (Melake et al 2012;De Giacomo et al 2002) 63.3-70 % of children were infected by H. pylori at/before 14 and 15 of age revealing high rate of infection at the first and second decades. The most common route of transmission is person-person contact, by either the oral-oral route or the fecal-oral route (Brown 2000).…”

Section: Introductionmentioning

confidence: 99%

Advanced trends in controlling Helicobacter pylori infections using functional and therapeutically supplements in baby milk

et al. 2015

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Helicobacter pylori is a common human pathogen infecting about 30 % of children and 60 % of adults worldwide. It is responsible for diseases such as gastritis, peptic ulcer and gastric cancer. H. pylori treatment based on antibiotics with proton pump inhibitor, but therapy failure is shown to be higher than 20 % and is essentially due to an increasing in prevalence of antibiotic-resistant bacteria, which has led to the search for alternative therapies. In this study, we discuss the usage of natural extracts mixture as alternative or complementary agents in controlling H. pylori infection so here, we focused on the plant extracts of (Cloves, Pepper, Cumin, Sage, Pomegranate peel, Ginger, Myrrh and Licorice). To that end, Phytochemical constituents detection like Tannins, Glycosides, Alkaloids, Flavonoids, Terpenoids, Saponins, Phenolic compounds, Reducing sugars, Volatile oils, Amino acids and Proteins was demonstrated. Each plant extract was examined individually or in combination for its antimicrobial activity against H. pylori. Out of the used extracts, four mixes were prepared and tested against H. pylori. The antibacterial activities of the four mixes, represented by the diameter of inhibition clear zone, recorded 21, 39, 23 and 28 mm. The most potent mix (mix2) was chosen and mixed with baby milk as a new combination for H. pylori infections treatment in babies.

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Section: Introductionmentioning

confidence: 99%

Advanced trends in controlling Helicobacter pylori infections using functional and therapeutically supplements in baby milk

et al. 2015

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“…Among otherwise healthy school children, 3.5%–27% have dyspepsia,1,2 6%–14% have irritable bowel syndrome,3 and up to 8% have functional constipation 4. In children with neurologic disorders, gastrointestinal dysfunction is even more common.…”

Section: Introductionmentioning

confidence: 99%

Magnet tracking allows assessment of regional gastrointestinal transit times in children

Hedsund¹,

Joensson²,

Gregersen³

et al. 2013

CEG

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BackgroundData on small intestinal transit time in healthy children are lacking, and normal values for gastric emptying and colonic transit time are sparse. Conventional methods, including radiopaque markers, scintigraphy, and PillCam™ involve radiation or require the child to swallow a large pill. The minimally invasive, radiation-free Motility Tracking System-1 (MTS-1) has been introduced for description of gastrointestinal motility in adults. The aim of the study was to evaluate the MTS-1 for assessment of gastrointestinal transit times and motility patterns in healthy children.MethodsTwenty-one healthy children (nine girls), median age 10 (range 7–12) years were included. For evaluation with MTS-1, a small magnetic pill was ingested and tracked through the gastrointestinal tract by a matrix of 16 magnetic sensors placed behind a nonmagnetic bed. The children were investigated for 8 hours after swallowing the magnetic pill and again for 4 hours the following morning. After leaving the unit, each child came back after every bowel movement to determine if the pill had been expelled.ResultsNineteen children could swallow the pill. Characteristic contraction patterns were identified for the stomach (three per minute), small intestine (9–11 per minute), and colon (4–5 per minute). Median total gastrointestinal transit time was 37.7 (range 9.5–95.8) hours, median gastric emptying time was 37 (range 2–142) minutes, median small intestinal transit time was 302 (range 164 to >454) minutes, and median colorectal transit time was 38.1 (range 5.6–90.0) hours.ConclusionMTS-1 allows minimally invasive evaluation of gastrointestinal motility in children. Use of the method is, however, restricted by the nonambulatory setup.

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“…H pylori is almost always acquired in childhood (usually before age 10 years), 9 and, if untreated, infection is lifelong. In the developing world, up to 70% of children are infected with H pylori by age 15 years ( Figure 1).…”

Section: Infection With H Pylori: Risk Factors and Acquisitionmentioning

confidence: 99%

“…Because of radioactivity risks, particularly in children, there are very few data on the use of 14 C-labeled urea breath tests in the pediatric population. Although the UBT has been studied in children, 9,[19][20][21][22] its diagnostic ability, especially in those younger than 3 years of age, may be limited by several factors. For example, performance of the test requires some level of oral-pharyngeal coordination, with children being more likely to retain the compound in the oropharynx that also harbors urease-producing organisms, thereby producing false-positive test results.…”

Section: Diagnosing H Pylori In Childrenmentioning

confidence: 99%

Helicobacter pylori infection: Detection, investigation, and management

Czinn

2005

The Journal of Pediatrics

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A Population‐Based Survey on Gastrointestinal Tract Symptoms and Helicobacter pylori Infection in Children and Adolescents

Abstract: Dyspeptic symptoms are frequent in children, and its association with H. pylori infection is more evident than with recurrent abdominal pain. The age at which the infection is acquired seems to be under 6 years of age.

Cited by 55 publications

References 29 publications

Advanced trends in controlling Helicobacter pylori infections using functional and therapeutically supplements in baby milk

Advanced trends in controlling Helicobacter pylori infections using functional and therapeutically supplements in baby milk

Magnet tracking allows assessment of regional gastrointestinal transit times in children

Helicobacter pylori infection: Detection, investigation, and management

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