A Possible Biodegradable Magnesium Implant Material

Abstract

The different hydrogen evolution rates for Mg immersed in simulated body fluid solutions with and without phosphates signify that the constituents of the body fluid could play different roles in the biodegradation of a magnesium implant. Currebtly, there is still a lack of fundamental understanding of the corrosion behavior of magnesium in the body fluid.

The Effect of Pre‐Processing and Grain Structure on the Bio‐Corrosion and Fatigue Resistance of Magnesium Alloy AZ31

“…However, the data points in the low frequency region showed too much scatter to signify the corrosion reaction mechanism, so they are not included . Nethertheless, the lack of the low frequency spectra does not affect the following discussion in this paper, as the low frequency EIS features are insignificant compared with the capacitive loop in the high frequency region [11] . Neglecting the low frequency spectra would not introduce significant error in the estimation of the corrosion rate in this study.…”

“…Indeed, pure magnesium without these alloying elements experiences a much faster biodegradation under similar testing conditions. [11] It was found [15] that in Hank's solution the rate of hydrogen evolution that reflects the biodegradation rate increases with time for pure magnesium, while for a magnesium alloy containing Al or Zn the biodegradation rate decreases with time. Thus the degradation behaviour of alloy AZ31 reported in this paper is in agreement with other studies [15] on biodegradation of magnesium alloys in a similar simulated body fluid.…”

Porous magnesium-based scaffolds for tissue engineering

“…Due to such collective properties, Mg based alloys can be employed as biocompatible, bioactive, and biodegradable scaffolds for load-bearing biomedical applications [25,26]. Such characteristics encourage employing biodegradable Mg and Mg alloys as lightweight metals for load bearing orthopaedic implants, which would remain in the body and keep mechanical stability over a time scale of 3-4 months, while the natural bone tissue heals [33,34].…”

Preparation and Characterization of Aminated Hydroxyethyl Cellulose-Induced Biomimetic Hydroxyapatite Coatings on the AZ31 Magnesium Alloy

“…Magnesium is a necessary element to human nutrition, and some scholars believe that magnesium and magnesium alloys are suitable as a biodegradable implant material [5,6]. Magnesium alloys are recoverable, light, and thermally conductive.…”