A practical guide to therapeutic drug monitoring in busulfan: recommendations from the Pharmacist Committee of the European Society for Blood and Marrow Transplantation (EBMT)

Domingos, Vera; Nezvalova-Henriksen, Katerina; Dadkhah, Adrin; Moreno-Martinez, Maria-Estela; Ben Hassine, Khalil; Pires, Vera; Kröger, Nicolaus; Bauters, Tiene; Hassan, Moustapha; Duncan, Nick; Kalwak, Krzysztof; Ansari, Marc; Langebrake, Claudia; Admiraal, Rick

doi:10.1038/s41409-024-02413-0

Bone Marrow Transplant

2024

DOI: 10.1038/s41409-024-02413-0

|View full text |Cite

A practical guide to therapeutic drug monitoring in busulfan: recommendations from the Pharmacist Committee of the European Society for Blood and Marrow Transplantation (EBMT)

Vera Domingos,

Katerina Nezvalova-Henriksen,

Adrin Dadkhah

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Preprint1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 123 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

A Practical Guide to Therapeutic Drug Monitoring in Busulfan: Recommendations from the Pharmacist Committee of the European Society for Blood and Marrow Transplantation (EBMT)

Admiraal,

Langebrake

2024

Preprint

View full text Add to dashboard Cite

Busulfan (Bu) is an important component of many conditioning regimens for allogeneic hematopoietic cell transplantation. The therapeutic window of Bu is well characterized, with strong associations between Bu exposure and the clinical outcome in adults (strongest evidence in myelo-ablative setting) and children (all settings). We provide an overview of the literature on Bu as well as a step-by-step guide to the implementation of Bu therapeutic drug monitoring (TDM). The guide covers the clinical, pharmacological, laboratory and administrative aspects of the procedure. Through this document, we aim to support centers in implementing TDM for Bu to further enhance the success rates of HCT and improve patient outcomes. The Pharmacist Committee of the European Society for Blood and Marrow Transplantation (EBMT) encourages all centers to perform TDM for Bu in the aforementioned indications.

show abstract

A Practical Guide to Therapeutic Drug Monitoring in Busulfan: Recommendations from the Pharmacist Committee of the European Society for Blood and Marrow Transplantation (EBMT)

Admiraal,

Langebrake

2024

Preprint

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

A practical guide to therapeutic drug monitoring in busulfan: recommendations from the Pharmacist Committee of the European Society for Blood and Marrow Transplantation (EBMT)

Cited by 1 publication

References 123 publications

A Practical Guide to Therapeutic Drug Monitoring in Busulfan: Recommendations from the Pharmacist Committee of the European Society for Blood and Marrow Transplantation (EBMT)

A Practical Guide to Therapeutic Drug Monitoring in Busulfan: Recommendations from the Pharmacist Committee of the European Society for Blood and Marrow Transplantation (EBMT)

Contact Info

Product

Resources

About