2021
DOI: 10.1016/j.vas.2021.100218
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A preliminary study comparing the sedative, cardiorespiratory, and histaminic-releasing effects of intramuscular and intravenous administration of pethidine (meperidine) with midazolam in healthy cats

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Cited by 4 publications
(3 citation statements)
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References 20 publications
(26 reference statements)
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“…The combination of 3 mg/ kg pethidine with 0.1 mg/kg midazolam in cats induced minimal cardiorespiratory depression, nausea and vomiting as side effects, besides a reasonably short duration (~30 mins) of sedation suitable for venepuncture, minor invasive procedures (ie, thoracentesis, abdominocentesis and cystocentesis) and other non-invasive procedures (ie, proper radiographic position) in cats, without a hangover after the end of the procedure. 30 However, the lack of any blood gas evaluation impedes assessment for possible ventilatory depression.…”
Section: Discussionmentioning
confidence: 99%
“…The combination of 3 mg/ kg pethidine with 0.1 mg/kg midazolam in cats induced minimal cardiorespiratory depression, nausea and vomiting as side effects, besides a reasonably short duration (~30 mins) of sedation suitable for venepuncture, minor invasive procedures (ie, thoracentesis, abdominocentesis and cystocentesis) and other non-invasive procedures (ie, proper radiographic position) in cats, without a hangover after the end of the procedure. 30 However, the lack of any blood gas evaluation impedes assessment for possible ventilatory depression.…”
Section: Discussionmentioning
confidence: 99%
“…A 1-week washout period was implemented between each administration. 16 The baseline sedation score (SS), [17][18][19] SBP, pulse rate (PR) and RR were measured 10 mins after the cat had become accustomed to the experimental environment. After completion of these measurements, the treatment was administered, and the time of administration (T0) was recorded.…”
Section: Study Design and Treatmentsmentioning
confidence: 99%
“…The sedation score was derived from previous published studies [17][18][19] and the specific methodology is detailed in Table 1. The extent of sedation was evaluated based on posture, resistance to positioning in lateral recumbency, resistance to extension of the left hindlimb and left knee, responsiveness to sound stimuli and reactions to air blowing.…”
Section: Sedation Scorementioning
confidence: 99%