2024
DOI: 10.18632/aging.205722
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A prognostic signature established based on genes related to tumor microenvironment for patients with hepatocellular carcinoma

Zhongfeng Cui,
Ge Li,
Yanbin Shi
et al.

Abstract: Background: Complex cellular signaling network in the tumor microenvironment (TME) could serve as an indicator for the prognostic classification of hepatocellular carcinoma (HCC) patients. Methods: Univariate Cox regression analysis was performed to screen prognosis-related TME-related genes (TRGs), based on which HCC samples were clustered by running non-negative matrix factorization (NMF) algorithm. Furthermore, the correlation between different molecular HCC subtypes and immune cell infiltration … Show more

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