À propos d’un cas de paludisme post-transfusionnel

The Epidemiology of Imported Malaria and Transfusion Policy in 5 Nonendemic Countries

“…This donor was subsequently found to be positive on the Diamed assay and IFAT (1/40). To date, this is the only case of TTM attributed to failure of the Lab 21 assay [38].…”

“…For Canada, the number of cases was provided by the Public Health Agency of Canada (Personal Communication, H. Zheng, Public Health Agency of Canada-July 18, 2012); species and country of origin, from the Québec Department of Public Health (province of Québec only) and the City or Toronto (country of origin for Toronto, ON, cases) [36]. Data concerning transfusion transmitted cases in the past 12 years were obtained from the CDC Malaria Reports [24][25][26][27][28][29][30][31][32], from published reports for England [37] and France [33,38], and from the investigators.…”

Malaria

“…Seit diesem Wechsel wurde ein Fall beschrieben, bei dem der Lab21-Test falsch negativ ausfiel. Nachuntersuchungen zeigten, dass der Spender sehr niedrige Antikörpertiter und Parasitenlast aufwies, sodass es auch in anderen Tests zu diskrepanten Ergebnissen kam [99,100]. In England wurde 1997 eine Antikörpertestung (enzymgekoppelter Immunadsorptionstest, EIA) implementiert, ab 2001 erfolgte eine Testung mittels IFAT und Lab21-Test in Kombination mit Spendebefragung [56,71,99].…”

Preventing transfusion‐transmitted malaria in France

“…The next TTM case yet-reported in France occurred in 2012 [7] and involved a donor native of Benin and living in France since 12 years, with no reported intercurrent travelling to malaria-endemic areas. An Ab test (Captia malaria ELISA, Trinity Biotech) performed on a 1st blood donation was negative.…”