À propos de deux cas de varicelle congénitale : plaidoyer pour la vaccination des femmes en âge de procréer

Bruel, H.; Jp, Chabrolle; Khoury, Emmanuelle; Poinsot, J.; Amusini, P.; Beurrier, J.

doi:10.1016/j.arcped.2003.12.016

Cited by 3 publications

(1 citation statement)

References 11 publications

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“…One of the most risky situations is chickenpox in unimmunized pregnant women [3]: it itself is at risk, in particular for severe pneumonia; but also his fetus, on the one hand between 13 and 20 weeks amenorrhea (AS) with the risk of embryo-fetopathy (growth retardation, cutaneous, skeletal and central and peripheral neurological damage) [ Figures 1,2] in approximately 2 % of cases [3]: and on the other hand in the week preceding childbirth or immediately after, with the risk in the newborn of developing severe neonatal chickenpox in 20 to 50% of cases. We offer a decision tree in the event of chickenpox disease [9].…”

Section: Introductionmentioning

confidence: 99%

Chickenpox infection in children, action to take

Bruel¹,

Pinquier²

2020

J Vaccines Immunol

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Section: Introductionmentioning

confidence: 99%

Chickenpox infection in children, action to take

Bruel¹,

Pinquier²

2020

J Vaccines Immunol

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Fetal varicella – diagnosis, management, and outcome

Mandelbrot

2012

Prenatal Diagnosis

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Fetal varicella syndrome (FVS) is due to transplacental infection by the Varicella zoster virus following maternal infection. The risks for the fetus and neonate depend on the timing. When varicella occurs around delivery, it often leads to disseminated neonatal varicella. When varicella occurs during pregnancy, transmission can occur, but is usually asymptomatic; some infants develop zoster postnatally and a few have FVS. Before 20 weeks' gestation, FVS can occur, with an incidence of about 1%. The lesions can affect the skin, limbs, central and autonomous nervous systems, eyes, cause calcifications, and growth retardation; mortality is high. Lesions typically follow one or several nerve territories, suggesting that damage results from in utero zoster following primary fetal infection. There has been little study of prenatal diagnosis of FVS. Serial ultrasound examination can detect various anomalies, magnetic resonance imaging can be of use to investigate for microphthamia and cerebral lesions, and amniocentesis can diagnose viral transmission. Prevention strategies include vaccination and post-exposure prophylaxis with immune globulin and/or antivirals. Perspectives for treating infected fetuses in utero require further research.

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À propos de la varicelle congénitale

Bruel¹,

2006

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À propos de deux cas de varicelle congénitale : plaidoyer pour la vaccination des femmes en âge de procréer

Cited by 3 publications

References 11 publications

Chickenpox infection in children, action to take

Chickenpox infection in children, action to take

Fetal varicella – diagnosis, management, and outcome

À propos de la varicelle congénitale

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