A prospective, comparative survey to investigate practitioners’ satisfaction with a cohesive, polydensified‐matrix^®, hyaluronic acid‐based filler gel with and without lidocaine for the treatment of facial wrinkles

Abstract

The lidocaine-containing dermal filler significantly reduced pain during and following treatment compared with the same preparation without lidocaine, without impact on administration, aesthetic outcome, or safety.

Hyaluronic acid gel based on CPM® technology with and without lidocaine: Is there a difference?

“…Since 2013, we have injected CPM ® gel with lidocaine for the same indications as with the gel without lidocaine. Although the gel was presented as perfectly identical to that without lidocaine, confirmed by most of the tests we presented herein, we had the same difference in feeling as when we participated in a study on the 3D Matrix ® gel Juvederm ® Ultra 3 with lidocaine, presented like Surgiderm ® with lidocaine by the manufacturer, in Europe .…”

“…At our clinic, the following devices and substances were used: 0.9% NaCl saline serum, 70° ethanol, Adson forceps, tape measure, Talens ® violet blue coloring, Petri dishes, urine cups, and Omnican ® 50 syringes with 30½G inserted needles for extracting Talens ® coloring substance and 70° ethanol …”

“…13 At our clinic, the following devices and substances were used: 0.9% NaCl saline serum, 70° ethanol, Adson forceps, tape measure, Talens ® violet blue coloring, Petri dishes, urine cups, and Omnican ® 50 syringes with 30½G inserted needles for extracting Talens ® coloring substance and 70° ethanol. 9,[12][13][14][15] For the cohesiveness test at our clinic, we collected 0.6 mL saline serum, colored with two drops of Talens ® stain, extracted using an Omnican ® 50 syringe, in the jar for urine analysis. Using a syringe tip without the needle, 0.2 mL of gel was then injected into the saline serum.…”

“…In 2011, the Belotero ® Balance CPM ® HA gel, without lidocaine, was approved by the USA Food and Drug Administration (FDA). In 2014, lidocaine was then added to the gel, and we have since performed several tests comparing gels with and without lidocaine . At present, CPM ® gel with lidocaine is still awaiting FDA approval.…”

Hyaluronic acid fillers with cohesive polydensified matrix for soft-tissue augmentation and rejuvenation: a literature review

“…In all but two studies, 31 , 32 the Belotero ® dermal fillers did not contain lidocaine, since the addition of lidocaine to the Belotero ® range is relatively recent (April 2014 for Belotero ® Basic/Balance and Belotero ® Intense, January 2015 for Belotero ® Volume).…”