A Prospective Multi-Center Clinical Trial Evaluating the Apogee System for the Treatment of Posterior Vaginal Wall and Apical Prolapse: A Sub-Analysis of Apical Extrusions with or without Concomitant Hysterectomy

Lukban, James; Erickson, Ty; Virelles, Moises A; Flaherty, James; Beyer, R.; Moore, R.D.; Hodroff, Marc A.

doi:10.1016/j.jmig.2008.09.138

Cited by 2 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Unpublished data has been presented on a subgroup of patients from the PROPEL Study in which a similar apical extrusion rate was found in those with (2.8%) and without (1.0%) hysterectomy at the time of Apogee with IntePro placement in the PC/A [35]. As reported by Collinet et al, hysterectomy with an inverted “T” colpotomy was an independent risk factor for extrusion in a sample of subjects receiving a Prolene transvaginal mesh [36].…”

Section: Discussionmentioning

confidence: 99%

“…The finding of prior hysterectomy as a risk factor for extrusion in subjects treated with Perigee is surprising, given that no such correlation was found between PC/A mesh placement employing Apogee in which contact between polypropylene and the apical scar may have been more common. Unpublished data has been presented on a subgroup of patients from the PROPEL Study in which a similar apical extrusion rate was found in those with (2.8%) and without (1.0%) hysterectomy at the time of Apogee with IntePro placement in the PC/A [ 35 ]. As reported by Collinet et al, hysterectomy with an inverted “T” colpotomy was an independent risk factor for extrusion in a sample of subjects receiving a Prolene transvaginal mesh [ 36 ].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Incidence of Extrusion Following Type I Polypropylene Mesh “Kit” Repairs in the Correction of Pelvic Organ Prolapse

Lukban

Beyer

Moore

2012

Obstetrics and Gynecology International

View full text Add to dashboard Cite

Introduction and Hypothesis. We sought to determine the mesh extrusion (vaginal exposure) rates and subject outcomes following IntePro (Type I polypropylene) mesh “kit” repairs for vaginal prolapse. Methods. Data were pooled from two prospective multicenter studies evaluating the safety and efficacy of the Perigee and Apogee (American Medical Systems, Minnetonka, Minn, USA) to treat anterior and posterior/apical prolapses, respectively. Extrusions involving the anterior compartment (AC) or posterior compartment/apex (PC/A) were recorded. Results. Two hundred sixty women underwent mesh placement, with a total of 368 mesh units inserted (173 in the AC and 195 in the PC/A). Extrusions were noted in 13 (7.5%) of AC implants and 27 (13.8%) of PC/A implants through 12 months. No difference was seen between those with and without extrusion in regard to anatomic cure, postoperative painor quality of life at 1 year. Conclusions. Extrusion had no apparent effect on short-term outcomes. Given the unknown long-term sequellae of vaginal mesh exposure, a thorough assessment of risks and benefits of transvaginal mesh placement should be considered at the time of preoperative planning.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%