A Prospective Observational Study on Prevalence of Hypothyroidism in a Tertiary Care Teaching Hospital

Swathi, N.; Kumar, Voleti Vijaya; Farjana, M.; Vardhan, M. Vishnu; Munendra, M.; Kumar, Granth

doi:10.22159/ijpps.2018v10i6.24958

Cited by 4 publications

(3 citation statements)

References 8 publications

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“…Hypothyroidism is still the most commonly diagnosed endocrine disorder in India, with a prevalence of 3.9-10.95% [1]. It occurs mainly in women of 21-40 years age [2]. Thyroid disease varies by geographic location, environmental factors, major radio nuclear activities, factors affecting the incidence and duration of iodine deficiency, the excess dietary iodine, and the population studied [3].…”

Section: Introductionmentioning

confidence: 99%

Assessment of Knowledge, Attitude, and Practice Regarding Hypothyroidism Among Infertile Women With Hypothyroidism

2020

Asian J Pharm Clin Res

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Objective: The study was designed to assess the knowledge, attitude, and practice (KAP) of hypothyroidism among infertile women with hypothyroidism. Methods: A cross-sectional analysis was performed in an outpatient environment of infertility centers. We used a validated questionnaire to assess hypothyroidism KAP. Using frequency counts (n) and percentages (%), discrete data were summarized. The Chi-square/Fisher test was used between groups to compare. Results: The mean age of participants was found to be 32±5.77 years. It was found that 72% of the subjects had poor knowledge, 44% were extremely concerned, and 81% were practicing with a moderate level of precaution. Among the consequences of hypothyroidism, 68% of the study subjects most properly-recognized menstrual disturbance, followed by 66%, 51%, and 48% of study subject properly-recognized weight gain, fatigue, and muscle aches/pain as a clinical manifestation of hypothyroidism. Most patients (98%) adhered to their medications. Nearly half of the study patients (45%) did not avoid cabbage, cauliflower, or soya. Conclusion: Our study highlighted the significance of investing appropriate time to provide patients with a comprehensive education to bridge the gaps in patient care. The findings also indicated that it be better for the understanding of the patients if health-care providers could provide patients with data sheets explaining the disease or having some pictorial/pamphlets about the disease’s reality and myths.

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Section: Introductionmentioning

confidence: 99%

Assessment of Knowledge, Attitude, and Practice Regarding Hypothyroidism Among Infertile Women With Hypothyroidism

2020

Asian J Pharm Clin Res

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“…[37,43] We observed that SCHypo (93.5%) is more prevalent than OVHypo (6.43%) among hypothyroid subjects. This was a very common observation which was noted by a number of studies, for instance a study from Andhra Pradesh, [47] showed 86.53% of SCHypo and 13.46% OVHypo. [25,27,29,36,45,48] Our overall prevalence for OVHypo was found to be 2.3% and its proportion among the other thyroid disorders is 5.6%.…”

Section: Discussionmentioning

confidence: 68%

How widespread is Thyroid Disorders among Patients undergoing Coronary Artery Bypass Grafting? A Study from Tertiary Care Hospital

Kahol¹,

Kathait²,

Mishra³

et al. 2022

APJHS

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Coronary artery bypass grafting (CABG) is the most commonly performed cardiac procedure and thyroid disorders (hypothyroidism and hyperthyroidism) are the most widespread endocrine diseases. Till date, there is no Indian study pertaining to prevalence of thyroid disorders among subjects undergoing CABG. The aim of this study was to determine the prevalence of thyroid disorders among subjects undergoing CABG in a tertiary care hospital. This is a prospective observational hospital-based study having 560 subjects who underwent CABG. Pre-operative thyroid tests were conducted of all the subjects. On the basis of this test, subjects were divided into groups, “Euthyroid” (normal thyroid status) and Thyroid subjects, that is, Subclinical Hypothyroidism (SCHypo), Overt Hypothyroidism (OVHypo), Subclinical Hyperthyroidism (SCHyper), and Overt Hyperthyroidism (OVHyper), based on thyroid function test. The proportion of the disorders was calculated. The study population included 560 subjects (Males: 457 females: 103). The overall prevalence of thyroid function abnormalities was 41.07%. The SCHypo was the most pervasive thyroid disorder (33.75%), followed by SCHyper (4.28%), OVHypo (2.32%), and OVHyper (0.7%). Highest number of thyroid subject (57.8%) was in 40–59 age group and lowest (0.86%) in 18–39. Thyroid was more prevalent among females (45/103) than in males (185/457). Among subjects undergoing CABG, SCHypo was most common followed by SCHyper, OVHypo, and OVHyper. Among the subjects undergoing CABG, maximum thyroid cases are in the age group of 60–79 with female preponderance.

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“…In India, approximately 42 million people suffer from thyroid disease. Hypothyroidism is clear state of myxedema which may lead to multisystem failure or subclinical condition [2]. Hypothyroidism is identified by evaluating the thyroid hormone level in the blood and treated by a synthetic thyroid hormone.…”

Section: Introductionmentioning

confidence: 99%

Acacia Senegal Bark Extract in Regulation of Hypothyroidism: An Experimental Approach

Jangid

Purohit

2019

Asian J Pharm Clin Res

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Objective: The objective of the present study was to evaluate the thyroid hormone stimulating efficacy of Acacia senegal (Gum Arabic) bark extract in 6-n-propyl-2-thiouracil (PTU)-induced hypothyroid albino rats.Methods: Ethanolic extract of A. senegal bark was given to PTU-induced hypothyroid albino rats at the dose of 500 mg/kg body weight. The animals were divided into control, PTU, and A. senegal bark extract treated and standard drug Eltroxin-treated groups for 60-day experimentation. The serum thyroxin levels, organ’s weight, and serum biochemistry were carried out.Results: Oral administration of A. senegal bark extract caused a highly significant increase (p≤0.001) in serum triiodothyronine (T3) and tetraiodothyronine (T4), and significant changes were also observed in organ’s weight with biochemical parameters as compared to hypothyroid albino rats and results were approximate to the standard drug Eltroxin.Conclusion: These results evaluate that ethanolic extract of A. senegal bark helps to compensate or increases the serum thyroxin level in management of hypothyroidism.

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A Prospective Observational Study on Prevalence of Hypothyroidism in a Tertiary Care Teaching Hospital

Cited by 4 publications

References 8 publications

Assessment of Knowledge, Attitude, and Practice Regarding Hypothyroidism Among Infertile Women With Hypothyroidism

Assessment of Knowledge, Attitude, and Practice Regarding Hypothyroidism Among Infertile Women With Hypothyroidism

How widespread is Thyroid Disorders among Patients undergoing Coronary Artery Bypass Grafting? A Study from Tertiary Care Hospital

Acacia Senegal Bark Extract in Regulation of Hypothyroidism: An Experimental Approach

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