1993
DOI: 10.1200/jco.1993.11.10.1852
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A prospective phase II study on photodynamic therapy with photofrin II for centrally located early-stage lung cancer. The Japan Lung Cancer Photodynamic Therapy Study Group.

Abstract: PDT with photofrin II has an excellent effect on patients with centrally located early-stage lung cancer who have limited tumor invasion extending over a small area (< or = 1 cm).

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Cited by 251 publications
(158 citation statements)
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“…2 Although it runs on 100 V current, the system is 49 ϫ 20 ϫ 40 cm in size, weighs 20 kg, and is easy to take into a sickroom. The power of the laser is easily adjusted, the wavelength of the light is stable (within 0.2 nm), and it is delivered through a quartz fiber.…”
Section: Laser Light Delivery Systemmentioning
confidence: 99%
See 1 more Smart Citation
“…2 Although it runs on 100 V current, the system is 49 ϫ 20 ϫ 40 cm in size, weighs 20 kg, and is easy to take into a sickroom. The power of the laser is easily adjusted, the wavelength of the light is stable (within 0.2 nm), and it is delivered through a quartz fiber.…”
Section: Laser Light Delivery Systemmentioning
confidence: 99%
“…The effectiveness of PDT for treatment of malignant tumors was established by Dougherty et al 1 in relation to metastatic skin lesions of breast carcinoma in 1975, and by Furuse et al 2 in regard to the treatment of lung cancer in 1993. The results of using PDT to treat early stage lung carcinoma showed a high complete remission rate.…”
mentioning
confidence: 99%
“…Overall 5-year survival rates were in the range of 56%-70% [97,100,101], with a disease-specific 5-year survival rate of 90% for CIS [97]. However, patients presenting with CIS are sparse, limiting the clinical impact of PDT for this disease.…”
Section: Endobronchial Cancermentioning
confidence: 99%
“…This therapeutic modality has been shown to be a promising alternative for treating early squamous cell cancers (SCC) in hollow organs (Edell and Cortese, 1992;Furuse et al, 1993;Grant et al, 1993;Hayata et al, 1993). In head and neck cancers, the advantage of PDT compared with other conventional modalities such as surgery, radiation therapy or chemotherapy, lies in the limited destruction of normal tissue surrounding the tumour, which reduces the risk of significant functional disorders such as dysphagia (Biel, 1995).…”
mentioning
confidence: 99%