“…• There is moderate quality evidence (high risk of bias) from seven studies (Abd-Alrahman 1999; Barlocher 2002; Dowd 1999; Martins 1976;Rosenorn 1983;Savolainen 1998;Xie 2007; N = 487) that the difference in complication rate between discectomy alone and iliac crest autograft is not statistically significant (OR 1.56; 95% CI 0.71 to 3.43; P = 0.27; see Figure 3). In the discectomy group, eight complications were reported (6 re-operations, 1 nerve lesion, 1 staphylococcus aureus infection); in the human bone graft group, thirteen complications (4 re-operations, 2 infection, 2 hematoma, 1 graft loosening, 1 iliac crest pain, 1 iliac crest fracture) were reported.…”