A Prospective Study Evaluating the Etiologic Spectrum in Patients with Dysphagia in Coastal Odisha Using Clinical Features and Endoscopy

Panigrahi, Subhendu; Khatua, Chitta Ranjan; Mishra, Debakanta; Parida, Pramod Kumar

doi:10.1055/s-0039-1693286

Cited by 5 publications

(3 citation statements)

References 13 publications

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“…[ 1 13 14 15 26 27 28 ] Among 28 patients with esophageal stricture, only 4 (14.3%) had esophageal stricture either peptic or secondary to active esophagitis, and this number is far less than that reported from Panigrahi et al . [ 29 ] stating corrosive stricture and Western data stating gastro-esophageal reflux disease (GERD) as the main etiologies of dysphagia. [ 12 30 ] These trends clearly indicate the esophageal growth as one of the most common reasons of dysphagia in our settings.…”

Section: Discussionmentioning

confidence: 99%

Etiological and clinical profiles of patients with dysphagia: A teaching institution experience

Goyal,

Jitender,

Garg

et al. 2024

Journal of Family Medicine and Primary Care

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Background: Dysphagia can involve any structure from the mouth to the lower esophageal sphincter. The etiologies vary from benign causes to malignant lesions. There is dearth of data regarding dysphagia in our population. Methods: A total of 208 patients with complaints of dysphagia were screened for the study. After ruling out neurological/local oropharyngeal causes of dysphagia, 200 patients with suspected esophageal dysphagia (ED) were recruited in the study. Dysphagia was graded as per the dysphagia scoring system. All patients underwent upper gastro-intestinal endoscopy and were evaluated for the presence of mechanical and non-mechanical causes of ED. Results: The mean age of patients with dysphagia was 53.8 ± 15.4 years. with males and females being 82 and 118, respectively. The mean duration of the symptom was 7.2 ± 10.6 months (median 3 months). Ninety-eight patients (49%) having dysphagia were in the age group of 56–65 years. The dysphagia score was 0 among 58, and 4 among 26 subjects. Foreign body sensation was the most frequent chief complaint in 90 (45%) patients. Ninety-six (48%) and 104 (52%) patients had mechanical and non-mechanical causes of dysphagia, respectively. Among mechanical causes of dysphagia, 68 patients (70.8%) had esophageal growth and 28 (29.2%) had esophageal stricture. Sixty-seven patients had squamous cell carcinoma. Among non-mechanical causes, 50 (48.1%) had globus sensation, 24 (23.1%) had hiatus hernia, and 16 (15.4%) functional dysphagia. Conclusion: Dysphagia is a common problem with varied etiologies. The esophageal growth and globus sensation are among the predominant causes of ED. We stress that all patients of dysphagia must be meticulously investigated.

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Section: Discussionmentioning

confidence: 99%

Etiological and clinical profiles of patients with dysphagia: A teaching institution experience

Goyal,

Jitender,

Garg

et al. 2024

Journal of Family Medicine and Primary Care

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“…A total of 216 consecutive patients admitted to the gastroenterology outpatient department with a history of dysphagia were included in the study. Benign strictures were diagnosed in 31.48% (corrosive injury in 70.59%, peptic stricture in 11.76%, postoperative strictures in 5.88%) and esophageal carcinomas in 23.62% [ 31 ].…”

Section: Discussionmentioning

confidence: 99%

Nutritional Status and the Outcomes of Endoscopic Stenting in Benign and Malignant Diseases of Esophagus

et al. 2023

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Background. Endoscopic stenting (ES) is a widely known method for palliative dysphagia treatment in esophageal strictures. Esophageal cancer is often associated with advanced malnutrition, which may increase the risk of complications of the procedure. The aim of this study was to evaluate complication rates and the impact of nutritional status on the outcomes of ES. Patients and Methods. A single-center retrospective study was conducted at Copernicus Hospital in Gdańsk, Poland. Adult patients who underwent endoscopic stenting between February 2014 and December 2018 were included. The influence of patient characteristics (age, sex, indications for esophageal stenting, and location of stenosis) and nutritional status (BMI, NRS 2002, GLIM, and dysphagia score) on complication rates and survival were analyzed. Results. Eighty-one patients (69% men) were enrolled in the study. In 69%, the indication for ES was malignancy (mainly esophageal cancer). The median dysphagia score significantly decreased from 2.8 to 0.6 after the procedure (p < 0.001). Complications were observed in 27% (n = 22) of the patients. Early complications were bleeding (2.5%), stent unexpansion (2.5%), and stent migration during the procedure (3.7%). There were no early fatal complications of the procedure. Late complications included: stent migration (6.2%), tissue overgrowth (6.2%), food impaction (2.2%), fistula formation (3.7%), bleeding (3.7%), and stent malposition (1.2%). A total of 76% of the participants scored ≥ 3 points in nutritional screening (NRS2002) and 70% were diagnosed with severe malnutrition (GLIM -stage 2). A stent diameter of < 2.2 cm compared with ≥ 2.2 was associated with a higher rate of migrations (15.5% vs. 2.5%). The median survival time in the malignant group was 90 days. Histopathological diagnosis and patients’ nutritional status (BMI, NRS 2002, GLIM, and dysphagia score) had no significant effect on complication rates and survival after esophageal stent insertion. Conclusions. Endoscopic stenting is a relatively safe procedure for the palliative treatment of esophageal strictures. Severe malnutrition, although common, does not affect the outcomes of the procedure.

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“…Dysphagia is a frequent complaint of patients presenting in GI clinics [7][8][9][10]. The causes of dysphagia of esophageal origin that are identified commonly are benign and malignant strictures of esophagus, reflux esophagitis, Schatzki's ring, compression occurring externally from a malignancy, disorders of motility, scleroderma and achalasia [11][12][13][14][15][16]. In some population-based studies, the rates of prevalence of dysphagia have been reported to be 17-25% with a peak in symptoms at the age of 40-49 years for both gender [17,18].…”

Section: Discussionmentioning

confidence: 99%

Endoscopic Findings and Their Association With Gender, Age and Duration of Symptoms in Patients With Dysphagia

Rashid

Bakht

Arslan³

et al. 2020

Cureus

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Introduction Dysphagia is highly prevalent in patients with a history of recurrent acid peptic disease. Endoscopy is the mainstay of diagnostic workup of these patients to reach underlying cause and appropriate subsequent treatment. The objective of the study was to determine the frequency of various types of endoscopic findings in patients with dysphagia and the association of these findings with gender, age and duration of symptoms. Methods This cross-sectional study was carried out in the Department of Gastroenterology of a tertiary care hospital in Rawalpindi, Pakistan. A total of 137 patients who presented with a history of dysphagia for at least two weeks were enrolled in the study. Duration of symptoms was noted, and all patients underwent upper gastrointestinal endoscopy to find out the cause of dysphagia. Tissue biopsies were obtained, and further histopathological examination was performed to correlate the findings with symptoms of dysphagia. Results A total of 137 patients were enrolled for six months. The mean age of the patients was 56.9 ± 17.44 years, and the mean duration of symptoms was 15.96 ± 12.31 weeks. There were 65 (47.4%) males and 72 (52.6%) females in the study. Majority of them, 123 (89.8%), presented with a short duration of symptoms that varied between 2-24 weeks and were mainly middle-aged (31-60 years) and old-aged (61-80 years). The most commonly observed endoscopic findings were esophageal stricture in 25 (18.2%), achalasia cardia in 20 (14.6%), esophageal mass in 12 (8.8%) and reflux esophagitis in 7 (5%) patients. No association was seen between age, gender and duration of symptoms and findings on the endoscopy. Conclusion Dysphagia is associated with many endoscopic findings that are not related to demographic variables and must be evaluated earlier to reduce further morbidity and mortality.

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A Prospective Study Evaluating the Etiologic Spectrum in Patients with Dysphagia in Coastal Odisha Using Clinical Features and Endoscopy

Cited by 5 publications

References 13 publications

Etiological and clinical profiles of patients with dysphagia: A teaching institution experience

Etiological and clinical profiles of patients with dysphagia: A teaching institution experience

Nutritional Status and the Outcomes of Endoscopic Stenting in Benign and Malignant Diseases of Esophagus

Endoscopic Findings and Their Association With Gender, Age and Duration of Symptoms in Patients With Dysphagia

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