A Prospective Study of HIV-Seropositive Asymptomatic Women of Childbearing Age in a Developing Country

Deschamps, Marie-Marcelle; Pape, Jean William; Desvarieux, Moïse; Williams-Russo, Pamela; Madhavan, Shantha; Ho, John L.; Johnson, Warren D.

doi:10.1097/00126334-199305000-00003

Cited by 39 publications

(31 citation statements)

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“…A look at antiretroviral agents, including ZDV recommended for preventing mother-to-infant HIV transmission, reveals that very little is known about their long-term effects on newborns and mothers. 261 As noted, studies conducted in the early 1990s provide contradictory evidence for whether a woman's pregnancy exacerbates HIV disease progression, [268][269][270] although recent studies found that it did not. 206,271 Further research is needed, however, and physicians caring for HIV-infected pregnant women should continue to report any unusual or adverse events, both fetal and obstetric, to the Antiretroviral Pregnancy Registry.…”

Section: Clinical Care Issues For Women With Hiv and Aidsmentioning

confidence: 99%

Clinical Care Issues for Women Living with HIV and AIDS in the United States

Marlink

Kao

Hsieh

2001

AIDS Research and Human Retroviruses

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As the number of women infected with HIV in the United States continues to increase, the medical community is faced with the challenge of providing adequate and appropriate care to them. This paper reviews key questions concerning the state of knowledge on the epidemiology, biology, and clinical care of women living with HIV and AIDS in the United States. Because heterosexual transmission accounts for a growing number of cases among women, biological factors and cofactors that may enhance women's susceptibility to HIV infection are also reviewed. HIV-related gynecological issues are presented separately to evaluate whether gynecological complications are distinct in HIV-uninfected and HIV-infected women. Questions of whether there are sex-specific differences in the efficacy and adverse effects of new antiviral agents are discussed. In addition, significant gaps are highlighted that still exist in our understanding of both the effects of HIV and HIV-related drugs upon pregnancy. Finally, the psychiatric stresses and complications that affect women living with HIV and AIDS are also discussed. In each section of this review, gaps in our knowledge of these issues are identified. To properly address these disparities in knowledge, not only do efforts to gather sex-specific biomedical data need to be more exacting, but there is a distinct need to conduct more sex-specific research concerning HIV.

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Section: Clinical Care Issues For Women With Hiv and Aidsmentioning

confidence: 99%

Clinical Care Issues for Women Living with HIV and AIDS in the United States

Marlink

Kao

Hsieh

2001

AIDS Research and Human Retroviruses

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“…Reassuringly there appears to be no significant difference in the natural history of HIV in women compared to men 230 and pregnancy does not accelerate the development of AIDS or death 231 • At present therefore, there is no conclusive evidence to avoid the combined contraceptive pill in HIV seropositive women but, on balance, it may be preferable to consider a progestogen only pill or an injectable progestogen.…”

Section: Barrier Contraceptionmentioning

confidence: 99%

Women, Contraception and STDs Including HIV

Carlin

Boag

1995

Int J STD AIDS

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Summary: It is estimated that eight million women are infected with the human immunodeficiency virus (HIV) worldwide. Heterosexual transmission is the predominant mode of HIV transmission on a global basis and is becoming increasingly important in the Western world.Women have long used contraceptives as a means of protection against an unwanted pregnancy, some of which may also protect against sexually transmitted disease (STD) including HIV.We review the relationship between contraceptive methods and STD acquisition and transmission; HIV acquisition and transmission; and the implications of contraceptive use, particularly regarding disease progression, in those women who are already infected with the virus.It is important for all women that protection against both unwanted pregnancy and HIV acquisition and transmission are considered together and not in isolation as nowhere is the argument for a broad based multi-disciplinary approach more cogent.

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“…1 Studies have examined the risk of vertical transmission and morbidity in infants born to HIV-positive women, but the effect of pregnancy on the health of HIV-positive women themselves is not well understood. Existing studies examining the relationship between pregnancy and the natural history of HIV disease have reached differing conclusions, [2][3][4][5][6][7][8][9] with the majority stating that pregnancy has little or no impact on the progression of HIV disease. 2,3,4,6 Many studies of the influence of pregnancy on HIV disease progression have focused on developed countries and have found either no effect or that pregnancy appears to delay disease progression.…”

Section: Introductionmentioning

confidence: 99%

“…Existing studies examining the relationship between pregnancy and the natural history of HIV disease have reached differing conclusions, [2][3][4][5][6][7][8][9] with the majority stating that pregnancy has little or no impact on the progression of HIV disease. 2,3,4,6 Many studies of the influence of pregnancy on HIV disease progression have focused on developed countries and have found either no effect or that pregnancy appears to delay disease progression. [9][10][11] The latter finding is probably due to the generally better health status and access to healthcare in pregnant vs. nonpregnant women.…”

Section: Introductionmentioning

confidence: 99%