A prospective study to assess the association of body mass index and contamination of urinalysis samples

Strawn, Matt; Xu, KT; Brodeur, Michael; Youngblood, Guy; Richman, Peter B.

doi:10.1016/j.ajem.2019.05.036

Cited by 2 publications

(2 citation statements)

References 19 publications

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“…It is unknown if genitourinary changes of menopause affect contamination of urine specimens. Previous research has demonstrated that overweight and obese female patients have an increased likelihood of providing a contaminated clean catch specimen, 9 also that women with pelvic organ prolapse would have increased rates of contaminated clean catch specimens 10 . Our study provides additional information for interpreting urine specimen results from 2 collection methodologies, as well as guidance for clinical scenarios specific to a urogynecology patient population.…”

Section: Discussionmentioning

confidence: 79%

Comparing Urine Specimen Collection Methods for Urinalysis and Culture Agreement: A Paired Sample Design

Hubb

Heit²

2021

Female Pelvic Med Reconstr Surg

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Objectives:The primary aim of this study was to determine if results from clean catch urine specimens agree with results from catheterized specimens in a urogynecology patient population. The secondary aim was to identify clinical scenarios in which catheterized specimens are preferred over clean catch specimens.Methods: Both a midstream clean catch and a catheterized specimen were obtained for each participant. Dipstick urinalysis was performed. If either specimen was positive for nitrites, leukocyte esterase, or blood then both were sent for urine culture.Kappa statistics were calculated to measure agreement between the paired specimen data for the total sample and for stratified samples. We agreed to accept clean catch results as preferable to catheterized results if the κ statistic was 0.7 or greater.Results: Three hundred forty-two participants were enrolled. For all participants, the agreement between the paired samples was strong for nitrite (κ = 0.884), moderate for blood and colony count (both κ = 0.656), weak for culture species (κ = 0.566), and minimal for leukocyte esterase (κ = 0.382). When data were stratified for menopause, vaginal estrogen use, body mass index, and prolapse, there were no clinical scenarios in which the κ values were consistently greater than our accepted value of 0.7. Conclusions:Our data indicate that catheterized urine specimens should be used in the evaluation of urinary tract infection or microscopic hematuria in the typical patient presenting to a urogynecology office who is often menopausal, overweight, and may have prolapse.

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Section: Discussionmentioning

confidence: 79%

Comparing Urine Specimen Collection Methods for Urinalysis and Culture Agreement: A Paired Sample Design

Hubb

Heit²

2021

Female Pelvic Med Reconstr Surg

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“…Similar results were obtained with contaminated urinalysis results in persons with obesity in a study conducted in the emergency department. 6 Mixed urine cultures pose a diagnostic challenge to most clinicians. In some cases, clinicians may continue broad antimicrobial treatment or may order repeat urine cultures to confirm the diagnosis, thus increasing laboratory workload, causing processing delays.…”

Section: Discussionmentioning

confidence: 99%

Investigating risk factors for urine culture contamination in outpatient clinics: A new avenue for diagnostic stewardship

Whelan

Nelson

Kim

et al. 2022

ASHE

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A prospective study to assess the association of body mass index and contamination of urinalysis samples

Cited by 2 publications

References 19 publications

Comparing Urine Specimen Collection Methods for Urinalysis and Culture Agreement: A Paired Sample Design

Comparing Urine Specimen Collection Methods for Urinalysis and Culture Agreement: A Paired Sample Design

Investigating risk factors for urine culture contamination in outpatient clinics: A new avenue for diagnostic stewardship

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