A Protic Ionic Liquid Catalyzes CO₂ Conversion at Atmospheric Pressure and Room Temperature: Synthesis of Quinazoline‐2,4(1H,3H)‐diones

Abstract

The chemical fixation of CO2 under mild reaction conditions is of significance from a sustainable chemistry viewpoint. Herein a CO2-reactive protic ionic liquid (PIL), [HDBU(+)][TFE(-)], was designed by neutralization of the superbase 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) with a weak proton donor trifluoroethanol (TFE). As a bifunctional catalyst for simultaneously activating CO2 and the substrate, this PIL displayed excellent performance in catalyzing the reactions of CO2 with 2-aminobenzonitriles at atmospheric pressure and room temperature, thus producing a series of quinazoline-2,4(1H,3H)-diones in excellent yields.

Protic Ionic Liquids: Evolving Structure–Property Relationships and Expanding Applications

“…Quinazoline-2,4(1H,3H)-diones were produced in excellent yields at room temperature and atmospheric pressure, and the PIL could be recovered and reused. 524 17.6. Condensation Reactions 17.6.1.…”

Electrocarboxylation of Dichlorobenzenes on a Silver Electrode in DMF

“…The first one is to create a low-carbon economic development model that conserves energy and controls energy from the source. The second method is to convert CO 2 into useful organic chemicals [2][3][4]. Continuous emission of CO 2 is expected to occur for a long time due to human dependence on fossil fuel.…”

Ionic liquids and supercritical carbon dioxide: green and alternative reaction media for chemical processes

“…Furthermore, heterocycles could be synthesized using ILs as both media and catalyst, and CO 2 as reactant. Zhao et al (2014) synthesized a protic IL [HDBU + ][TFE -] by neutralization of the superbase 1,8-diazabicyclo[5.4.0]undec-7-ene with a weak proton donor trifluoroethanol and used as solvent and catalyst for synthesize quinazoline-2,4(1H,3H)-diones using 2-aminobenzonitriles and CO 2 and the substrates. Two reactants were activated simultaneously on the same IL catalyst, and high yields of products were achieved under mild reaction conditions.…”