2022
DOI: 10.1016/j.crmicr.2022.100113
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A putative short-chain dehydrogenase Rv0148 of Mycobacterium tuberculosis affects bacterial survival and virulence

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Cited by 3 publications
(1 citation statement)
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“…Earlier studies have reported that the interaction of Rv2159c with PknI occurs at the Ala49 and Gly50 amino acid residues [17]. Rv2159c has also been reported to interact with Rv0148, a putative short chain dehydrogenase involved in intermediary metabolism, homeostasis, virulence, and drug resistance of M. tuberculosis [18,19]. Gene knockdown studies on Rv2159c report reduced in vitro survival of the bacteria and a higher level of sensitivity to oxidative stress, compared to the wild type strain [14].…”
Section: Introductionmentioning
confidence: 99%
“…Earlier studies have reported that the interaction of Rv2159c with PknI occurs at the Ala49 and Gly50 amino acid residues [17]. Rv2159c has also been reported to interact with Rv0148, a putative short chain dehydrogenase involved in intermediary metabolism, homeostasis, virulence, and drug resistance of M. tuberculosis [18,19]. Gene knockdown studies on Rv2159c report reduced in vitro survival of the bacteria and a higher level of sensitivity to oxidative stress, compared to the wild type strain [14].…”
Section: Introductionmentioning
confidence: 99%