A quantitative alternative to the Goutallier classification system using Lava Flex and Ideal MRI techniques: volumetric intramuscular fatty infiltration of the supraspinatus muscle, a cadaveric study

Trevino, Jose H.; Gorny, Krzysztof R.; Gomez-Cintron, Angel; Zhao, Chunfeng; Giambini, Hugo

doi:10.1007/s10334-019-00774-y

Cited by 9 publications

(21 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We hypothesized that the superior spatial resolution of IOP acquisitions may explain its higher performance to detect intratumoral fatty changes in HCC compared with CSE‐MRI. However, as the IOP images were generated using a dual‐echo method, the magnetic field inhomogeneity from the LAVA‐Flex method might have caused an overestimation of fatty content 31 . Hence, IOP results could have been biased to some extent due to several confounding factors.…”

Section: Discussionmentioning

confidence: 99%

Accuracies of Chemical Shift In/Opposed Phase and Chemical Shift Encoded Magnetic Resonance Imaging to Detect Intratumoral Fat in Hepatocellular Carcinoma

Rajlawot

Jiang

Zhou

et al. 2021

Magnetic Resonance Imaging

View full text Add to dashboard Cite

Background Magnetic Resonance Imaging (MRI) being a noninvasive modality may help in preoperative evaluation of intratumoral fat in hepatocellular carcinoma (HCC) using chemical shift encoded (CSE) MRI and in‐/opposed‐phase (IOP) imaging sequences. Purpose To compare the diagnostic accuracy of chemical shift encoded fat fraction at three different flip angles (FAs) using quantitative chemical shift encoded MRI (CSE‐MRI) with in‐/opposed phase (IOP) imaging to evaluate intratumoral fat in HCC. Study Type Retrospective. Population Eighty‐six patients with 87 pathology proven HCCs. Field Strength/Sequence IOP (LAVA‐Flex) and CSE‐MRI (IDEAL IQ) a three‐dimensional spoiled gradient‐echo pulse sequences acquired at 3 T. Assessment Regions of interest (ROIs) were manually drawn by two observers in the tumors to measure mean fat fractions. Surgical specimens were reassessed for intratumoral fat content. Signal‐to‐noise ratio (SNR) and contrast‐to‐noise ratio (CNR) were assessed for CSE‐MRI sequence at FA 3°, 8°, and 9°. Statistical Tests Intraclass correlation coefficient (ICC) was expressed in terms of inter‐ and intra‐observer agreements. Receiver operating characteristic curve analysis was performed for the diagnostic performance followed by combined metric of both. SNR/CNR were analyzed by Kruskal–Wallis test. Results Excellent inter‐ and intra‐observer agreements (ICC >0.95, P < 0.001) were observed for both IOP and CSE‐MRI. IOP (86.4%) showed higher sensitivity than CSE‐MRI at FA 3° (72.5%), FA 8° (76.4%) and FA 9° (76.3%). In contrast, the specificity for CSE‐MRI at FA 3° (86%), FA 8° (87%), and FA 9° (87%) were greater than IOP (72%). A combined metric of IOP and CSE‐MRI derived fat fractions at FA 8° gave highest AUC of 87% and accuracy of 86%. SNR and CNR for CSE‐MRI were significantly higher at FA 8° and FA 9° than FA 3° (P < 0.05). Data Conclusion IOP and quantitative CSE‐MRI are both feasible methods to detect intratumoral fat in HCC with higher accuracy and SNR for CSE‐MRI at FA 8° and 9°. Level of Evidence 3 Technical Efficacy Stage 2

show abstract

Section: Discussionmentioning

confidence: 99%

Accuracies of Chemical Shift In/Opposed Phase and Chemical Shift Encoded Magnetic Resonance Imaging to Detect Intratumoral Fat in Hepatocellular Carcinoma

Rajlawot

Jiang

Zhou

et al. 2021

Magnetic Resonance Imaging

View full text Add to dashboard Cite

show abstract

“…Fat-only, water-only images (LAVA-Flex), and fat fraction images (Ideal IQ) were used to identify the adipose tissue along the posteromedial tibial border. LAVA-Flex and Ideal IQ were previously used to evaluate the fat fraction of the rotator cuff [ 22 ]. The adipose tissue showed low signal intensity on water-only images and high signal intensity on fat-only images [ 22 ].…”

Section: Discussionmentioning

confidence: 99%

“…LAVA-Flex and Ideal IQ were previously used to evaluate the fat fraction of the rotator cuff [ 22 ]. The adipose tissue showed low signal intensity on water-only images and high signal intensity on fat-only images [ 22 ]. Therefore, we defined tissue with low signal intensity on water-only images and high signal intensity on fat-only images as the adipose tissue (Fig.…”

Section: Discussionmentioning

confidence: 99%

“…The soft tissue enclosing the adipose tissue was also identified. LAVA-Flex can accurately separate fat and water by utilising the difference in chemical shifts between protons in water and fat molecules [ 22 ]. Signals from fat are suppressed on water-only imaging, whereas signals from water are suppressed on fat-only imaging.…”

Section: Methodsmentioning

confidence: 99%

“…Thus, the adipose tissue was defined based on high signal intensity on fat-only imaging as well as low signal intensity on water-only imaging. Additionally, the soft tissue enclosing the adipose tissue was identified using in-phase and water-only images [ 8 , 22 ].

Fig.…”

Section: Methodsmentioning

confidence: 99%

See 2 more Smart Citations

Presence of adipose tissue along the posteromedial tibial border

et al. 2021

View full text Add to dashboard Cite

Purpose The flexor digitorum longus and posterior tibial tendon as well as the perforating veins are located along the distal posteromedial tibial border. Adipose tissue may surround these structures and possibly play a role in reducing mechanical stress. This study aimed to examine the adipose tissue along the posteromedial tibial border via magnetic resonance imaging (MRI), ultrasound, and gross anatomical examination. Methods The lower legs of 11 healthy individuals were examined every 3 cm from the medial malleolus using MRI and ultrasound. The fat fraction was calculated using fat fraction images. In addition, the gross anatomy of the flexor digitorum longus origin and adipose tissue along the posteromedial tibial border was examined in seven fresh cadavers. The fat fraction was compared at different heights along the posteromedial tibial border and in Kager’s fat pads; we also compared the height of the flexor digitorum longus origin and adipose tissue. Results In vivo, the adipose tissue was identified along the entire posteromedial tibial border using MRI and ultrasound. There was no significant difference in fat fraction between Kager’s fat pads and the adipose tissue along the posteromedial tibial border, except at the 6 cm mark. All seven cadavers presented adipose tissue along the posteromedial tibial border, significantly more distal than the flexor digitorum longus origin. Conclusion The adipose tissue was identified along the posteromedial tibial border via MRI, ultrasound, and gross anatomical examination; thus, this tissue may play a role in reducing friction and compressive stress in tendons.

show abstract

Associations of Quantitative and Qualitative Muscle Parameters With Second Hip Fracture Risk in Older Women: A Prospective Cohort Study

Zhang,

Ge,

Liu

et al. 2023

JBMR Plus

View full text Add to dashboard Cite

Older women with a first hip fracture exhibit heightened susceptibility and incidence of second fracture and potentially severe consequences. This prospective study was to compare the predictive power of qualitative and quantitative muscle parameters for a second hip fracture in older women with a first hip fracture. A total of 206 subjects were recruited from the longitudinal Chinese Second Hip Fracture Evaluation study. Hip computed tomography (CT) scans were obtained immediately after the first fracture. Muscle fat infiltration was assessed according to the Goutallier classification qualitatively. Quantitative parameters included cross‐sectional area and density of gluteus maximus (G.MaxM) and gluteus medius and minimus (G.Med/MinM) muscles. CT X‐ray absorptiometry was used to measure the areal bone mineral density (aBMD) of the contralateral femur. Cox proportional hazards models were used to compute hazard ratios (HR) of second hip fracture risk. The mean age of subjects was 74.9 (±9.5) years at baseline. After 4.5 years, 35 had a second hip fracture, 153 without a second hip fracture, and 18 died. Except for the combined G.MinM Goutallier grade 3 and 4 groups before adjustment for covariates (HR = 5.83; 95% confidence interval [CI] 1.49–22.83), there were no significant HRs for qualitative classification to predict a second hip fracture. Among quantitative metrics, after adjustment for covariates, G.Med/MinM density was significant in the original (HR = 1.44; CI 1.02–2.04) and competing risk analyses (HR = 1.46; CI 1.02–2.07). After additional adjustment for femoral neck (FN) aBMD, G.Med/MinM density remained borderline significant for predicting a second hip fracture in competing risk analysis (HR = 1.43; CI 0.99–2.06; p = 0.057). Our study revealed that Goutallier classification was less effective than quantitative muscle metrics for predicting hip second fracture in this elderly female cohort. After adjustment for FN aBMD, G.Med/MinM density is a borderline independent predictor of second hip fracture risk. © 2023 The Authors. JBMR Plus published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research.

show abstract

A quantitative alternative to the Goutallier classification system using Lava Flex and Ideal MRI techniques: volumetric intramuscular fatty infiltration of the supraspinatus muscle, a cadaveric study

Cited by 9 publications

References 30 publications

Accuracies of Chemical Shift In/Opposed Phase and Chemical Shift Encoded Magnetic Resonance Imaging to Detect Intratumoral Fat in Hepatocellular Carcinoma

Accuracies of Chemical Shift In/Opposed Phase and Chemical Shift Encoded Magnetic Resonance Imaging to Detect Intratumoral Fat in Hepatocellular Carcinoma

Presence of adipose tissue along the posteromedial tibial border

Associations of Quantitative and Qualitative Muscle Parameters With Second Hip Fracture Risk in Older Women: A Prospective Cohort Study

Contact Info

Product

Resources

About