Phys. Chem. Chem. Phys.
 2023
DOI: 10.1039/d3cp01723k
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A quantum chemical study on the anti-SARS-CoV-2 activity of TMPRSS2 inhibitors

Akihiro Kondo
1
,
Kazuhiro Fujimoto
2
,
Takeshi Yanai
3

Abstract: Nafamostat and camostat are known to inhibit the spike protein-mediated fusion of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by forming a covalent bond with the human transmembrane serine protease...

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