A Randomised Control Trial to Ascertain if Postoperative Antibiotics Are Necessary Following Laparoscopic Appendicectomy in Nonperforated Appendicitis

Abstract

Background: The most frequent cause of severe abdominal discomfort is acute appendicitis. Prophylactic antibiotics should be used as directed to reduce the risk of postoperative surgical site infections (SSIs). There is no denitive recommendation, though, for how long to use antibiotics. There has only been one preoperative prophylactic dose several randomised control trials strongly suggest. Therefore, the goal of the study was to ascertain if postoperative antibiotics were necessary following laparoscopic appendix surgery for nonperforated appendicitis. Methods: A total of 52 nonperforated appendicitis patients were separated into two groups and underwent laparoscopic appendectomy. Patients in group B (n=26) received three postoperative doses of antibiotics in addition to the one preoperative dose given to group A's (n=26) patients. Regular investigations, such as Complete blood count, blood urea, serum creatinine, and other tests like an abdominal ultrasound were also carried out. After a laparoscopic appendicectomy, the surgical incision was examined to check for any evidence of postoperative SSI after 48, 72, and 7 days. Results: Group A had a mean age of 30.6± 10.5 years compared to group B's mean age of 30.7 ±9.5 years (p=0.75). Right iliac fossa pain was the initial complaint of every subject in the research. Grade III SSIs occurred in 0ne patient in group A (4%) and one patient in group B (4%) and were treated conservatively. The difference in the incidence of SSIs between the two groups was statistically negligible (p=1.000). Conclusions: After a laparoscopic appendicectomy, prophylactic postoperative doses of antibiotics offer no additional advantage over a single preoperative dosage in terms of preventing postoperative SSIs