ObjectiveBlood‐based biomarkers and neuroimaging techniques have improved our understanding of the underlying biology of eating disorders (EDs) and have increased our diagnostic portfolio.MethodThis editorial accompanies an article collection on novel biological approaches to treat EDs.ResultsThe collection covers intermittent theta burst stimulation, therapeutic drug monitoring, pharmacological treatments (olanzapine, metreleptin, psychedelics, and anti‐inflammatory medications), microbiome‐based treatments such as pro‐ and prebiotics, as well as individually tailored treatment approaches for EDs.DiscussionResearch of brain areas and bodily systems that are related to memory, emotions and immune function will hopefully expand the biological treatment options for people with EDs.