2023
DOI: 10.1016/j.jagp.2022.10.002
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A Randomised Placebo-Controlled Study of Purified Anthocyanins on Cognition in Individuals at Increased Risk for Dementia

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Cited by 10 publications
(3 citation statements)
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“…A randomised placebo-controlled trial of the effect of purified anthocyanins on cognition in individuals at increased risk for dementia has been undertaken [ 294 ]. A phase II clinical trial (ClinicalTrials.gov, NCT0341903) also assessed intervention strategies to prevent or delay the onset of dementia, and a further phase III trial of anthocyanins is also planned [ 295 ].…”
Section: Flavonoid Clinical Trialsmentioning
confidence: 99%
“…A randomised placebo-controlled trial of the effect of purified anthocyanins on cognition in individuals at increased risk for dementia has been undertaken [ 294 ]. A phase II clinical trial (ClinicalTrials.gov, NCT0341903) also assessed intervention strategies to prevent or delay the onset of dementia, and a further phase III trial of anthocyanins is also planned [ 295 ].…”
Section: Flavonoid Clinical Trialsmentioning
confidence: 99%
“…Consequently, dietary supplements rich in ANTs could prove beneficial in preventing and managing MetS. Moreover, ANTs have demonstrated potential in dementia treatment ( Bergland et al, 2019 ), improving specific cognitive functions and impacting cholesterol and triglyceride levels ( Aarsland et al, 2023 ). However, confirming these benefits requires larger and more rigorous studies.…”
Section: Discussionmentioning
confidence: 99%
“…The trial included 206 participants with mild cognitive impairment or cardiometabolic disorders who received 320 mg/day of naturally purified anthocyanins, including malvidin, for 24 weeks. Although there was no significant difference in episodic memory at the end of the study, statistically significant differences in slopes were observed [174]. Another trial, registered as NCT01746303, evaluated the effects of long-term supplementation of blueberry powder containing Vaccinium species, a source of anthocyanins, including malvidin [162,163], on older adults with cognitive complaints.…”
Section: Neuroprotective Effects Of Malvidin and Its Derivativesmentioning
confidence: 99%