A randomized clinical trial to arrest dentin caries in young children using silver diamine fluoride

Mabangkhru, Sirinan; Duangthip, Duangporn; Chu, Chun Hung; Phonghanyudh, Araya; Jirarattanasopha, Varangkanar

doi:10.1016/j.jdent.2020.103375

Cited by 65 publications

(80 citation statements)

References 24 publications

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“…Our findings were consistent with multiple studies, where high parental acceptance of their children's esthetics after SDF had been reported as well (17,22,23). Nevertheless, applying SDF on primary teeth of children up to 72 months old with high dmft scores and/or history of uncooperative behavior was more tolerated by parents than applying it on permanent teeth of older cooperative children with less dmft scores (24)(25)(26).…”

Section: Discussionsupporting

confidence: 92%

Parental Satisfaction After Using Silver Diamine Fluoride on Their Children’s Primary Teeth: A Randomized Clinical Trial

ElGhandour

El-Tekeya

Sharaf

2021

Alexandria Dental Journal

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BACKGROUND: Despite the effectiveness of silver diamine fluoride (SDF) in arresting caries, black staining of carious lesions is a major drawback. OBJECTIVE: To assess parental satisfaction after using SDF versus atraumatic restorative treatment (ART) to manage ECC in their children. MATERIALS AND METHODS:A randomized controlled clinical trial with patient reported outcomes; 100 children with ECC (2-5 years) were equally and randomly divided into two groups; Experimental group (N=50, n=268) received 38% SDF; Control group received ART (N=50, n=286). Parental satisfaction was assessed after 2 weeks using 4-item, 5-level, Likert-scale questionnaire. Quantitative data were represented using mean, and standard deviation (SD). Qualitative variables were displayed using frequency and percentages. Monte Carlo simulation method for Pearson's chi square statistics was applied to compare both groups regarding parental satisfaction. Significance level was set at P value ≤ 0.05. RESULTS: Eighty percent of parents/guardians strongly agreed, agreed or were neutral regarding their children's esthetics after SDF versus 98% after ART (P=0.06). All SDF parents/guardians strongly agreed or agreed it was an easy procedure versus 30% among ART group (P<0.0001). Among SDF parents/guardians, 96% reported the procedure to be pain free versus 74% in ART group (P= 0.008). Among SDF parents/guardians, 88% "strongly agreed" that the taste of received treatment was acceptable to their children versus 82% in ART group. (P= 0.614). CONCLUSION: Parental satisfaction regarding esthetics and taste was comparable after SDF and ART. Significantly more SDF parents/guardians viewed the procedure easy and pain free.

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Section: Discussionsupporting

confidence: 92%

Parental Satisfaction After Using Silver Diamine Fluoride on Their Children’s Primary Teeth: A Randomized Clinical Trial

ElGhandour

El-Tekeya

Sharaf

2021

Alexandria Dental Journal

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“…Thailand had initially imported SDF from Japan (Saforide) for research purposes and caries control in some remote areas with high prevalence of ECC. Studies of effectiveness on arresting dentinal carious lesions, optimum frequency of application, and the cost-effectiveness of SDF in the Thai population since 2009 have confirmed the positive results reported in other countries [59][60][61]. In 2017, the Dental Association of Thailand launched a guideline for using fluoride, including SDF, suggesting SDF application semiannually on dentinal carious lesions until caries arrest for patients with severe ECC, uncooperative behaviors, or compromised health conditions; followed by another guideline on caries diagnosis and management released in 2018, which recommended SDF as an alternative treatment of dental caries (ICDAS 5 and 6) in primary teeth when access to dental care was limited as well as root caries in permanent teeth [22].…”

Section: Thailandmentioning

confidence: 60%

Global Oral Health Policies and Guidelines: Using Silver Diamine Fluoride for Caries Control

Gao

Amarquaye

Arrow

et al. 2021

Front. Oral. Health

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Silver diamine fluoride (SDF) was developed in Japan in the 1960s. It is a clear solution containing silver and fluoride ions. Because of its anti-bacterial and remineralizing effect, silver diamine fluoride has been used in managing dental caries for decades worldwide. This paper aims to summarize and discuss the global policies, guidelines, and relevant information on utilizing SDF for caries management. SDF can be used for treating dental caries in most countries. However, it is not permitted to be used in mainland China. Several manufacturers, mainly in Australia, Brazil, India, Japan, and the United States, produce SDF at different concentrations that are commercially available around the world. The prices differ between contents and brands. Different government organizations and dental associations have developed guidelines for clinical use of SDF. Dental professionals can refer to the specific guidelines in their own countries or territories. Training for using SDF is part of undergraduate and/or postgraduate curriculums in almost all countries. However, real utilization of SDF of dentists, especially in the private sector, remains unclear in most places because little research has been conducted. There are at least two ongoing regional-wide large-scale oral health programs, using SDF as one of the components to manage dental caries in young children (one in Hong Kong and one in Mongolia). Because SDF treatment does not require caries removal, and it is simple, non-invasive, and inexpensive, SDF is a valuable strategy for caries management in young children, elderly people, and patients with special needs. In addition, to reduce the risk of bacteria or virus transmission in dental settings, using SDF as a non-aerosol producing procedure should be emphasized under the COVID-19 outbreak.

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“…Regarding failure, group II, comparison revealed statistical significant difference at 9 months and at 12 months. The following outcomes were considered to indicate treatment failure a yellow and, soft lesion, pain, or infection On the other hand, it found that high failure rate was in SDF group .The only explanation for this is the younger age group ,higher caries experience, compromised oral-health related behaviours (31) .…”

Section: Discussionmentioning

confidence: 99%

Pain, New Caries and Failure of Carious Primary Teeth after Application of Silver Diamine Fluoride Versus Sodium Fluoride Varnish: A Randomized Clinical Trial

Rehim¹,

Waly²,

Abdelgawad³

et al. 2021

IJPHRD

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Background:The aim of this study was assessment of the pain, new caries and failure of carious primary teeth after application of silver diamine fluoride versus sodium fluoride varnish immediately after application and after 3,6,9,12, months.Methods: This study was performed on 62 children with 255 carious primary teeth. After proper selection according to eligibility criteria and proper diagnosis. They were randomly allocated (1:1) into two groups. Group I (SDF): 38% Silver Diamine Fluoride and group II (NAF): 5% Sodium Fluoride Varnish. Assessment of postoperative pain, new caries,and failure at baseline, after 3,6,9,12, months.Results: Independent t-test was performed to compare between both groups and revealed that group II was significantly higher than group I after 9 and 12 months regarding postoperative pain, new caries, and failure. Also, strong positive significant correlation between failure and pain, and between failure and new caries was found using Spearman`s correlation coefficient test.Conclusions: SDF application isa successful alternative conservative treatment which eliminate the need to general anesthesia. Also, it is inexpensive, fast, and pain-free procedure but it causes discoloration. It`s successful results regardingstopping progression of new caries compensate its drawbacks such as discoloration.

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A randomized clinical trial to arrest dentin caries in young children using silver diamine fluoride

Cited by 65 publications

References 24 publications

Parental Satisfaction After Using Silver Diamine Fluoride on Their Children’s Primary Teeth: A Randomized Clinical Trial

Parental Satisfaction After Using Silver Diamine Fluoride on Their Children’s Primary Teeth: A Randomized Clinical Trial

Global Oral Health Policies and Guidelines: Using Silver Diamine Fluoride for Caries Control

Pain, New Caries and Failure of Carious Primary Teeth after Application of Silver Diamine Fluoride Versus Sodium Fluoride Varnish: A Randomized Clinical Trial

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