A randomized comparison of intradermal and intramuscular vaccination against hepatitis B virus in incident chronic hemodialysis patients

Charest, Andre F.; McDougall, James; Goldstein, Marc B.

doi:10.1053/ajkd.2000.19099

Cited by 80 publications

(76 citation statements)

References 24 publications

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“…The response rate (peak antibody titer Ͼ1,000 IU/liter) was similar in both groups (97% versus 90%), and vaccination appeared effective in this patient population (23,82). Current recommended dose of recombinant hepatitis B vaccine in patients with end-stage liver and renal disease waiting transplantation is 40 g in at least three repeated doses.…”

Section: Hepatitis Bmentioning

confidence: 75%

Vaccinations for Adult Solid-Organ Transplant Recipients: Current Recommendations and Protocols

Duchini¹,

Goss²,

et al. 2003

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Recipients of solid-organ transplantation are at risk of severe infections due to their life-long immunosuppression. Despite emerging evidence that vaccinations are safe and effective among immunosuppressed patients, most vaccines are still underutilized in these patients. The efficacy, safety, and protocols of several vaccines in this patient population are poorly understood. Timing of vaccination appears to be critical because response to vaccinations is decreased in patients with end-stage organ disease and in the first 6 months after transplantation. For these reasons, the primary immunizations should be given before transplantation, as early as possible during the course of disease. Vaccination strategy should include vaccination of household contacts and health care workers at transplant centers unless contraindicated. No conclusive data are available on the use of immunoadjuvants and screening for protective titers. Most vaccines appear to be safe in solid-organ transplantation recipients, but live vaccines should be avoided until further studies are available. The risk of rejection appears minimal. Recommended vaccines include pneumovax, hepatitis A and B, influenza, and tetanus-diphtheria. We outline specific protocols and recommendations in this particular patient population. Specific contraindications exist for other vaccines, such as yellow fever, oral polio vaccine, bacillus Calmette-Guerin, and vaccinia. We conclude that solid-organ recipients will benefit from consistent immunization practices. Further studies are recommended to improve established protocols in this patient population

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Section: Hepatitis Bmentioning

confidence: 75%

Vaccinations for Adult Solid-Organ Transplant Recipients: Current Recommendations and Protocols

Duchini¹,

Goss²,

et al. 2003

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show abstract

“…The results are at substantial discrepancy with previous studies. 10,11,12 However, a previous study comparing IM ministration with ID inoculation of the vaccine demonstrated similar results. 13 Yet the aggregate ID antigen dose was higher than that devised for the current study.…”

Section: Low Response To Intradermal Hepatitis B Vaccination In Incidmentioning

confidence: 59%

Baixa resposta da vacinação intradérmica contra hepatite B em pacientes incidentes em hemodiálise

Medeiros¹,

Figueiredo²,

Poli-de-Figueiredo³

et al. 2011

J. Bras. Nefrol.

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“…KBH hastalarında hepatit B aşılamasına yeterli cevap alınabilmesi için yüksek doz ve daha sık enjeksiyon yapılması önerilmiştir [10,18]. İmmün cevabı artırmak için çift doz aşılama yapılması, düşük antikor titresi elde edilirse booster doz yapılması [19][20][21][22][23], enjeksiyon şeklinin değiştirilmesi (intradermal veya intramüsküler), immün sistemi indükleyen ajanların eklenmesi [24][25][26][27] ve hepatit A ve B aşısının kombine verilmesi [28] gibi çeşitli yöntemler uygulanmıştır. [7] tarafından yapılan bir metaanalizde diyaliz türünün aşı yanıtı üzerine etkisinin olmadığı, genç hastalarda aşı yanıtının daha yüksek olduğu bildirilmiştir.…”

Section: Discussionunclassified

Hemodiyaliz ve periton diyalizi hastalarının Hepatit B aşısına karşı cevaplarının karşılaştırılması

Koçkara¹,

Candan²,

Hüzmelí³

et al. 2013

CMJ

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A randomized comparison of intradermal and intramuscular vaccination against hepatitis B virus in incident chronic hemodialysis patients

Cited by 80 publications

References 24 publications

Vaccinations for Adult Solid-Organ Transplant Recipients: Current Recommendations and Protocols

Vaccinations for Adult Solid-Organ Transplant Recipients: Current Recommendations and Protocols

Baixa resposta da vacinação intradérmica contra hepatite B em pacientes incidentes em hemodiálise

Hemodiyaliz ve periton diyalizi hastalarının Hepatit B aşısına karşı cevaplarının karşılaştırılması

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