2019
DOI: 10.18203/2320-1770.ijrcog20194206
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A randomized controlled trial of sublingual Misoprostol - 600µg versus intravenous Oxytocin - 10IU in prevention of post partum hemorrhage during cesarean section

Abstract: Background: Mortality related to pregnancy and childbirth causes half a million women around the world to die annually. About 35% of these deaths are from postpartum hemorrhage (PPH). Prevention of PPH has been advised by the WHO by the use of Oxytocin 10 IU IM or IV and Misoprostol 600 µg in low resource settings in vaginal delivery. However there have been only a few reports on the use of Misoprostol during cesarean section. The best route and dose of Misoprostol is still being debated.Methods: One hundred w… Show more

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Cited by 2 publications
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“…The effect of Oxytocin is reduced in myometrium of women with Oxytocin-augmented labor; however, it is still superior to the other uterotonics. 2,3 Various routes and doses of Oxytocin have been studied. Ten IU Intramuscular injection, 10 IU intravenous infusion, and10 IU intravenous bolus of Oxytocin in the third stage of labor for prevention of postpartum hemorrhage have been used.…”
Section: Introductionmentioning
confidence: 99%
“…The effect of Oxytocin is reduced in myometrium of women with Oxytocin-augmented labor; however, it is still superior to the other uterotonics. 2,3 Various routes and doses of Oxytocin have been studied. Ten IU Intramuscular injection, 10 IU intravenous infusion, and10 IU intravenous bolus of Oxytocin in the third stage of labor for prevention of postpartum hemorrhage have been used.…”
Section: Introductionmentioning
confidence: 99%