A Randomized Controlled Trial of High-Viscosity 2-Octyl Cyanoacrylate Tissue Adhesive versus Sutures in Repairing Facial Wounds Following Mohs Micrographic Surgery

Sniezek, Patrick J.; Walling, Hobart W.; DeBloom, James R.; Messingham, Michael J.; VanBeek, Marta; Kreiter, Clarence D.; Whitaker, Duane C.; Arpey, Christopher J.

doi:10.1111/j.1524-4725.2007.33199.x

Cited by 27 publications

(22 citation statements)

References 28 publications

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“…Higher viscosity is advantageous in reducing the risk of migration of the adhesive away from the wound and thus may improve wound cosmesis. [7] Within 5-10 days, as the wound re-epithelialises, the adhesive generally sloughs off. [7] Premature sloughing of the adhesive might result from topical ointment and frequent cleansing of wounds treated with OCA.…”

Section: Discussionmentioning

confidence: 99%

Cutaneous wound closure materials: An overview and update

Al-Mubarak

Al-Haddab

2013

J Cutan Aesthet Surg

135

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Introduction:On a daily basis, dermasurgeons are faced with different kinds of wounds that have to be closed. With a plethora of skin closure materials currently available, choosing a solution that combines excellent and rapid cosmetic results with practicality and cost-effectiveness can be difficult, if not tricky.Objectives:We aimed to review the available skin closure materials over the past 20 years and the scientific claims behind their effectiveness in repairing various kinds of wounds.Materials and Methods:The two authors independently searched and scrutinised the literature. The search was performed electronically using Pub Med, the Cochrane Database, Google Scholar and Ovid as search engines to find articles concerning skin closure materials written since 1990.Conclusion:Many factors are involved in the choice of skin closure material, including the type and place of the wound, available materials, physician expertise and preferences, and patient age and health. Evidence-based main uses of different skin closure materials are provided to help surgeons choose the appropriate material for different wounds.

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Section: Discussionmentioning

confidence: 99%

Cutaneous wound closure materials: An overview and update

Al-Mubarak

Al-Haddab

2013

J Cutan Aesthet Surg

135

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“…Tissue adhesive glues have been used for many years to treat small wounds and cuts. Various recent studies have shown that adhesive glues can be successfully applied to different mucosa and skin, as in the treatment of aphthous ulcers [5], lip closure [6], facial wounds after Mohs surgery [7], and nail bed injuries [8]. Other studies have shown successful use of adhesive glues in obstetrics and gynecology such as skin closure of Pfannenstiel incision at the end of cesarean section and repair of evulsion of clitoris [9, 10].…”

Section: Introductionmentioning

confidence: 99%

Using Adhesive Glue to Repair First Degree Perineal Tears: A Prospective Randomized Controlled Trial

Feigenberg

Maor‐Sagie

Zivi

et al. 2014

BioMed Research International

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Our objective was to evaluate the effectiveness of adhesive glue in repairing first degree perineal tears. We conducted a noninferiority prospective, randomized, controlled trial comparing adhesive glue with traditional suturing. Each case was evaluated immediately after birth and after the puerperium. The two-sample t-test and the Mann-Whitney nonparametric test were applied to compare quantitative variables between the treatment groups. The chi-squared test and Fisher's exact test were used to assess the association between qualitative variables. A total of 102 women participated, 28 in the suture arm and 74 in the adhesive glue arm. While cosmetic and functional results of adhesive glue use were not inferior to suturing, the use of adhesive glue was associated with a shorter procedure, less need for local anesthetic, less pain, and greater satisfaction. Our results suggest a novel approach for the repair of common postpartum first degree lacerations. The use of adhesive glue achieves cosmetic and functional results equal to traditional suturing and offers some immediate advantages for the patient. While further clinical trials are needed to validate our results, it is important to inform obstetrician of the possible use of adhesive glue in these very common clinical scenarios. This trial is registered with NCT00746707.

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“…3 Another study investigated the use of a liquid adhesive, high-viscosity 2-octyl cyanoacrylate compared with superficial sutures for repair of Mohs facial defects and found similar cosmetic results. 4 Although our study is the first to compare superficial sutures with adhesive strips for repair of cheek defects, one study compared superficial sutures with adhesive strips and tissue adhesive (octylcyanoacrylate) for skin closure after phlebectomy. There was no difference in cosmetic outcome at 1 year, but faster closure (although not statistically significant) and decreased expense was achieved with adhesive strips.…”

Section: Discussionmentioning

confidence: 99%

Layered closure versus buried sutures and adhesive strips for cheek defect repair after cutaneous malignancy excision

Plotner

Mailler-Savage

Adams

et al. 2011

Journal of the American Academy of Dermatology

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A Randomized Controlled Trial of High-Viscosity 2-Octyl Cyanoacrylate Tissue Adhesive versus Sutures in Repairing Facial Wounds Following Mohs Micrographic Surgery

Abstract: HVOCA tissue adhesive is cosmetically equivalent to epidermal sutures in the linear repair of facial wounds following MMS. This technique represents an additional option for Mohs surgeons.

Cited by 27 publications

References 28 publications

Cutaneous wound closure materials: An overview and update

Cutaneous wound closure materials: An overview and update

Using Adhesive Glue to Repair First Degree Perineal Tears: A Prospective Randomized Controlled Trial

Layered closure versus buried sutures and adhesive strips for cheek defect repair after cutaneous malignancy excision

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