2022
DOI: 10.1016/j.jtcme.2022.01.007
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A randomized double blinded placebo controlled clinical trial for the evaluation of green coffee extract on immune health in healthy adults

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Cited by 5 publications
(4 citation statements)
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“…IgG is the most prevalent antibody type present in all bodily fluids and contributes significantly to humoral immunity ( 19 ). IgG serves as the primary antibody in re-immune response and possesses various functions, including phagocytosis, neutralization of toxins and viruses, mediation of antibody-dependent cell-mediated cytotoxicity (ADCC), and activation of the classical pathway of complement ( 20 ).…”
Section: Immunoglobulinmentioning
confidence: 99%
“…IgG is the most prevalent antibody type present in all bodily fluids and contributes significantly to humoral immunity ( 19 ). IgG serves as the primary antibody in re-immune response and possesses various functions, including phagocytosis, neutralization of toxins and viruses, mediation of antibody-dependent cell-mediated cytotoxicity (ADCC), and activation of the classical pathway of complement ( 20 ).…”
Section: Immunoglobulinmentioning
confidence: 99%
“…However, consumption of excessive sugar without caffeine promoted Th17 responses and exacerbated inflammation in a mouse model of EAE 10 . Coffee extract enhances natural killer (NK) cell activity and monocyte phagocytosis and inhibits monocyte chemoattractant protein 1 (MCP‐1)‐induced monocyte migration 11 . However, the complete molecular mechanism underlying the association between coffee consumption and immune remodeling remains unclear.…”
Section: Introductionmentioning
confidence: 99%
“…Research on the use of various types of natural products as immunomodulators has been carried out, including the immunomodulatory effect of the ethanol extract of the sponge Melophlus sarasinorum on phagocytic activity of macrophage cells in male Balb/C mice at doses of 300 mg/kg BW and 400 mg/kg BW [18]; alginic oligosaccharides (osa) produced from alginate from Sargassum crassifolium [19]; green coffee extract reduce inflammation and modulation of immunological [20]; dried lemon peel improves antioxidant activity, immune response and modulates immuno-antioxidant genes [12]; and the role of a natural immunomodulator (Aloe vera) in the cellular and humoral immune system [11]. The immune system maintains the balance of immune homeostasis.…”
Section: Introductionmentioning
confidence: 99%
“…However, when the Covid 19 virus weakens the immune system, an imbalance in the immune response occurs. Nutrients derived from natural ingredients play an important role in regulating immune homeostasis [20]. The general public and health professionals need to be educated about the potential of natural ingredients as immunomodulators.…”
Section: Introductionmentioning
confidence: 99%