A rapid assay for detecting antibody against leucocytozoonosis in chickens with a latex agglutination test using recombinant R7 antigen

Ito, Akira; Gotanda, Tohru

doi:10.1080/03079450400025372

Cited by 7 publications

(6 citation statements)

References 17 publications

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“…Several diagnostic serological tests have been developed to detect antibodies against L. caulleryi in chickens [ 73 , 333 , 335 , 392 , 393 , 394 ], but they have not been developed for other Leucocytozoon species.…”

Section: Resultsmentioning

confidence: 99%

Insights into the Biology of Leucocytozoon Species (Haemosporida, Leucocytozoidae): Why Is There Slow Research Progress on Agents of Leucocytozoonosis?

Valkiūnas

Iezhova

2023

Microorganisms

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Blood parasites of the genus Leucocytozoon (Leucocytozoidae) only inhabit birds and represent a readily distinct evolutionary branch of the haemosporidians (Haemosporida, Apicomplexa). Some species cause pathology and even severe leucocytozoonosis in avian hosts, including poultry. The diversity of Leucocytozoon pathogens is remarkable, with over 1400 genetic lineages detected, most of which, however, have not been identified to the species level. At most, approximately 45 morphologically distinct species of Leucocytozoon have been described, but only a few have associated molecular data. This is unfortunate because basic information about named and morphologically recognized Leucocytozoon species is essential for a better understanding of phylogenetically closely related leucocytozoids that are known only by DNA sequence. Despite much research on haemosporidian parasites during the past 30 years, there has not been much progress in taxonomy, vectors, patterns of transmission, pathogenicity, and other aspects of the biology of these cosmopolitan bird pathogens. This study reviewed the available basic information on avian Leucocytozoon species, with particular attention to some obstacles that prevent progress to better understanding the biology of leucocytozoids. Major gaps in current Leucocytozoon species research are discussed, and possible approaches are suggested to resolve some issues that have limited practical parasitological studies of these pathogens.

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Section: Resultsmentioning

confidence: 99%

Insights into the Biology of Leucocytozoon Species (Haemosporida, Leucocytozoidae): Why Is There Slow Research Progress on Agents of Leucocytozoonosis?

Valkiūnas

Iezhova

2023

Microorganisms

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“…These include agar gel precipitation (Morii 1972), counter-immunoelectrophoresis (Fujisaki et al 1980), immunofluorescence (Fujisaki et al 1981;Isobe and Akiba 1982), an enzyme-linked immunosorbent assay (ELISA) Suzuki 1986, 1987a, b), immunoblot analysis (Isobe et al 1998), and a latex agglutination test using recombinant R7 antigen (Ito and Gotanda 2005). Similar tests have not been developed for other species of Leucocytozoon.…”

Section: Diagnosismentioning

confidence: 99%

“…Chickens that have recovered from primary infections of L. caulleryi are resistant to reinfection (Morii et al 1986(Morii et al , 1989, although young chickens are less resistant than older ones (Morii and Kitaoka 1970). IgM and IgG antibodies are involved in immunity (Isobe and Suzuki 1987b) as well as cell-mediated responses (Nakata et al 2003;Ito and Gotanda 2005). Complete protection against L. caulleryi is achieved by immunization with a recombinant R7 vaccine which is expressed against second-generation meronts (Ito and Gotanda 2005).…”

Section: Natural Resistance and Immunitymentioning

confidence: 99%

“…IgM and IgG antibodies are involved in immunity (Isobe and Suzuki 1987b) as well as cell-mediated responses (Nakata et al 2003;Ito and Gotanda 2005). Complete protection against L. caulleryi is achieved by immunization with a recombinant R7 vaccine which is expressed against second-generation meronts (Ito and Gotanda 2005).…”

Section: Natural Resistance and Immunitymentioning

confidence: 99%

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Leucocytozoonosis

Forrester¹,

Greiner²

2008

Parasitic Diseases of Wild Birds

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“…On the other hand, it is also clear that some parasites can be cryptic and indistinguishable using solely microscopy ( Sehgal et al., 2006 , Valkiūnas et al., 2010 , Palinauskas et al., 2015 ). In addition, there have been some efforts to use immunological methods for the detection of avian haemosporidians ( Jarvi et al., 2002 , Ito and Gotanda, 2005 , Palmer et al., 2013 ), but the development of specific antibodies to avian blood parasite proteins would be a major asset for immunohistochemistry and cell sorting approaches.…”

Section: Introductionmentioning

confidence: 99%

Manifold habitat effects on the prevalence and diversity of avian blood parasites

Sehgal

2015

International Journal for Parasitology: Parasites and Wildlife

133

135

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Habitats are rapidly changing across the planet and the consequences will have major and long-lasting effects on wildlife and their parasites. Birds harbor many types of blood parasites, but because of their relatively high prevalence and ease of diagnosis, it is the haemosporidians – Plasmodium, Haemoproteus, and Leucocytozoon – that are the best studied in terms of ecology and evolution. For parasite transmission to occur, environmental conditions must be permissive, and given the many constraints on the competency of parasites, vectors and hosts, it is rather remarkable that these parasites are so prevalent and successful. Over the last decade, a rapidly growing body of literature has begun to clarify how environmental factors affect birds and the insects that vector their hematozoan parasites. Moreover, several studies have modeled how anthropogenic effects such as global climate change, deforestation and urbanization will impact the dynamics of parasite transmission. This review highlights recent research that impacts our understanding of how habitat and environmental changes can affect the distribution, diversity, prevalence and parasitemia of these avian blood parasites. Given the importance of environmental factors on transmission, it remains essential that researchers studying avian hematozoa document abiotic factors such as temperature, moisture and landscape elements. Ultimately, this continued research has the potential to inform conservation policies and help avert the loss of bird species and threatened habitats.

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A rapid assay for detecting antibody against leucocytozoonosis in chickens with a latex agglutination test using recombinant R7 antigen

Cited by 7 publications

References 17 publications

Insights into the Biology of Leucocytozoon Species (Haemosporida, Leucocytozoidae): Why Is There Slow Research Progress on Agents of Leucocytozoonosis?

Insights into the Biology of Leucocytozoon Species (Haemosporida, Leucocytozoidae): Why Is There Slow Research Progress on Agents of Leucocytozoonosis?

Leucocytozoonosis

Manifold habitat effects on the prevalence and diversity of avian blood parasites

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