A rapid organ recovery program for non-heart-beating donors

Light, Jimmy A.; Kowalski, Adam; Sasaki, Truman M.; Barhyte, Diana Young; Ritchie, W.O.; Gage, Fred; Harviel, J. Duncan

doi:10.1016/s0041-1345(97)01019-1

Cited by 35 publications

(20 citation statements)

References 4 publications

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“…This perfusion technique is nowadays the most widespread method applied to perfuse these organs before their extraction. Nevertheless, high DGF rates have been reported using this technique 113, 14, 22,33,37,46,48,54].…”

Section: Introductionmentioning

confidence: 99%

Normothermic recirculation reduces primary graft dysfunction of kidneys obtained from non-heart-beating donors

Valero¹,

Cabrer²,

Oppenheimer³

et al. 2000

Transplant Int

145

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Our aim was to analyze the short-and long-term function of kidneys procured from non-heartbeating donors (NHBD) by means of three techniques: in situ perfusion (ISP), total body cooling (TBC) and normothermic recirculation (NR). (52 Yo) showed delayed graft function (DGF) and 9 (16 %) showed primary non function (PNF). The actuarial graft survival rate was 76.4 Yo at 1 year and 56 YO at 5 years. The patient survival rate was 89.3 YO at 5 years. Incidence of DGF and PNF was significantly lower in kidneys perfused with NR than those with ISP or TBC ( P < 0.01). Duration of DGF was shorter in kidneys obtained through TBC than in kidneys obtained with ISP (P < 0.05).In conclusion, NR reduces the incidence of DGF and may be considered the method of choice for kidney procurement from NHBD.

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Section: Introductionmentioning

confidence: 99%

Normothermic recirculation reduces primary graft dysfunction of kidneys obtained from non-heart-beating donors

Valero¹,

Cabrer²,

Oppenheimer³

et al. 2000

Transplant Int

145

View full text Add to dashboard Cite

show abstract

“…In the late 1990s, Washington Hospital Center implemented a protocol to retrieve organs from patients who suffered fatal trauma. 6 Over a 3-year period, this group obtained organs from 19 donors. During the same period, 27 patients became organ donors after brain death in that hospital.…”

Section: Experiences With Dcd Involving the Ed And Emsmentioning

confidence: 99%

“…1 Although the New York City protocol has two separate teams, 20 this is not practical in all cases. 6 Furthermore, such a distinction does not prevent the resuscitating team from considering the value of further resuscitation versus potential transplantation.…”

Section: Ethical Concerns Regarding Uncontrolled Dcdmentioning

confidence: 99%

“…Although this is often done, 6,20 it does not always happen. 46 However, both to preserve support for uncontrolled DCD, as discussed above, and to assure that the community is comfortable with the questions noted above regarding the dead-donor rule and presumed consent, the community must be involved.…”

Section: Ethical Concerns Regarding Dcds Specific To the Edmentioning

confidence: 99%

“…Several European health care systems have implemented protocols to allow DCD in both of these settings, and some U.S. cities have piloted similar protocols. [4][5][6][7][8] Although emergency physicians (EPs) will likely have little involvement with inpatient DCD protocols and cases, these extended protocols directly involve EPs. Indeed, EPs will likely lead the way in implementing these protocols and even determining how widespread and accepted they are.…”

mentioning

confidence: 99%

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