A Rare Case in Emergency: Herpes Zoster Ophtalmicus

Kavalcı, Cemil

doi:10.25149/jcrm.v8i3.218

Cited by 1 publication

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“…Overall, while there was an absence of comprehensive, nationwide data on HZ incidence in Turkey, 39 case reports or series, detailing numerous HZ-related complications and accompanying treatment strategies, were identified ([ 56 – 94 ]; Supplementary Table 1). Among these case studies, HZ ophthalmicus (HZO), characterized by the reactivation of VZV in the ophthalmic nerve, affecting regions around the eye, was the most common complication described (12 out of 43 patients described) [ 60 , 62 , 64 , 66 , 70 , 72 , 76 , 79 , 80 , 89 , 91 , 92 ]. Other reported HZ-related complications included PHN, Ramsay Hunt syndrome, segmental zoster paresis, VZV encephalitis, orbital apex syndrome, Ogilvie’s, complex regional pain syndrome, Horner’s syndrome, polymyalgia rheumatica, and brachial plexopathy, among others (Supplemental Table 1).…”

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confidence: 99%

Herpes Zoster Burden of Disease and Clinical Management in Turkey: A Comprehensive Literature Review

Badur,

Senol,

Azap

et al. 2023

Infect Dis Ther

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Introduction Herpes zoster (HZ), or shingles, is caused by the reactivation of varicella zoster virus (VZV) and typically presents as an acute, painful dermatomal rash, but can lead to long-term, distressing complications such as postherpetic neuralgia (PHN). Increasing trends in HZ cases are evident globally among the aging population; however, reviews investigating the epidemiology and clinical management of HZ in Turkey are lacking. Therefore, a literature review of local studies in Turkey was conducted to identify the data available and identify gaps in the literature. Methods Literature searches were carried out in PubMed and local journals to retrieve published articles that reported surveillance data, seroepidemiology, patient outcomes, or clinical management related to HZ or VZV in Turkey until April 30, 2022. Studies included primary data reports, case studies, secondary data reviews, and epidemiological studies in healthy or at-risk populations; HZ was the primary focus of the review. Results No studies reported VZV or HZ epidemiological data at a national level. One large retrospective study in Istanbul reported that HZ incidence rates significantly increased in adults 18–44 years of age between 2011 and 2019. Four single-center studies reported the proportion of dermatological patients with HZ at 0.43–1.56%. PHN was the most common reported complication, occurring in 8–58.9% of patients with HZ. However, out of 39 identified case reports, HZ ophthalmicus was the most frequently reported complication. Two studies highlighted poor disease awareness and risk perception of HZ among Turkish citizens. Conclusion Overall, there were limited comprehensive epidemiological data on HZ in Turkey. However, the abundance of case studies on HZ complications indicates a strong disease presence and diverse clinical management in Turkey. Further research will be important to understand the impact of HZ, increase disease awareness, and support the introduction of new preventative strategies. Supplementary Information The online version contains supplementary material available at 10.1007/s40121-023-00849-3.

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