A rare case of epilepsy and acute pancreatitis induced by severe paraquat poisoning

Abstract

Paraquat can lead to injury of multiple organs. As there is no specific treatment for paraquat poisoning, it represents a serious clinical problem. Antioxidants are required to treat oxidative stress in paraquat poisoning and paraquat-induced injury. In this study, we report on successful treatment of a rare case of epilepsy and acute pancreatitis caused by paraquat poisoning. A 29-year-old woman at our hospital presented with a 13-day history of nausea and vomiting after ingesting 20 mL of paraquat (20% W/V). After therapies, the symptoms were controlled. The patient remained asymptomatic during 1 year of follow-up.

Delayed death following paraquat poisoning: three case reports and a literature review

“…Epilepsy and acute pancreatitis are also induced by ingesting 20 ml of PQ (20% W/V), which was related to PQ-produced OS or free radicals. 28 Nausea, vomiting, and a severe substernal burning sensation are indicated after accidental poisoning caused by ingesting approximately 100 ml of PQ (60% solution) concentration. 29 Nausea, vomiting, discomfort, and neutropenia were observed in a 15-year-old girl, who ingested a small quantity of wine full of PQ.…”

“…49 In addition, epilepsy or convulsion was investigated in clinical case reports and studies. 28,29,50 Therefore, PQ-induced neurotoxicity is a matter of concern and should be prevented or treated in intoxicated patients. These findings indicated that PQ poisoning patients should be followed up for a long time after discharge from a hospital.…”