A rare case of important and recurrent abnormal uterine bleeding in a post partum woman caused by cavernous hemangioma: a case report and review of literature

Abstract

The cavernous hemangioma is a rare benign vascular tumor. About 50 cases of this disease were found in the literature over the last century and only 9 cases of cavernous hemangioma on the pregnant uterus were published it comes into cavernous or capillary form. The symptomatology is not unequivocal and when it occurs during pregnancy or postpartum, it causes life-threatening cataclysmic hemorrhage. Antenatal diagnosis is difficult and requires a multidisciplinary approach with pathologists, radiologists and gynecologists to avoid these complications or unnecessary hysterectomies. The diagnosis is histological. Hysterectomy is possible after failure of conservative treatment means. We report a rare case, a novel mixed cavernous hemangioma of the body associated with a capillary hemangioma of the cervix in a patient of 28 years 5th visors with recurrent genital bleeding in the postpartum period leading to a hysterectomy.

Postpartum hemorrhage and prolonged hyperfibrinolysis as complications of uterine cavernous hemangioma: a case report and literature review

“…If a rupture occurs in either condition, it can cause persistent vaginal bleeding or massive hemorrhage, even shock. Severe pregnancy complications such as postpartum hemorrhage, advanced postpartum hemorrhage, DIC, and thrombosis, have been reported in less than 20 cases worldwide [9,[11][12][13]. Amniotic fluid embolization may occur due to increased blood vessel crosssectional area [3], and spontaneous abortion, premature birth and fetal growth restriction have been reported in association with the condition [14,15].…”

Malformación venosa del útero

“…They are lesions that should be suspected in women of reproductive age and postmenopausal stage with unexplained vaginal bleeding (8). Symptoms are variable, asymptomatic cases may occur or may present with abdominal pain, fertility disorders, pregnancy-related complications (6), and bleeding that can vary, from abnormal vaginal bleeding, menometrorrhagia, postcoital spotting and postmenopausal bleeding (1).…”

“…but the use of this term is discouraged, since these lesions do not represent a proliferative neoplasm as its name indicates (2). The exact incidence of the entity is unknown, due to the low number of reported cases (6).…”

“…It usually occurs on the head and neck, extremities and trunk (4), but rarely within the uterus (5), where it can affect any layer of the uterine wall, especially the myometrium. Most are discovered incidentally, but can present with abnormal vaginal bleeding or be associated with gynecological and obstetric complications (6). They are found at any age, without predominance for any decade (the youngest patient described was a 14-year-old girl) (7) and should be suspected in patients with a history of infections, curettage, therapeutic abortions, pelvic surgery, endometrial carcinoma or Gestational trophoblastic disease (8).…”

lncRNA CASC9 regulates cell migration and invasion in hemangioma endothelial cells by targeting miR-125a-3p/Nrg1

“…About 75%–80% of HA patients are females, and HA often occurs about at birth 2 weeks after the birth of a child 2. Severe HA causes a heavy physical and mental burden to patients and their family members, especially due to the disfigured skin lesions, which affect the function and life of the skin 2,3. Severe HA is difficult to treat even in today’s medical field.…”