A Ratiometric Fluorescent Probe for Selective Detection of Hypochlorite Anion

Abstract

A new fluorescent probe based on rhodamine and naphthalimide was synthesized for the discrimination of hypochlorite anion. Upon addition of NaClO, the emission intensities ratio (I576 nm/I528 nm) of the probe 1 increased quickly accompanied with the obvious change of color. The probe 1 also exhibited highly selectivity and fast response to hypochlorite anion. Furthermore, the newly proposed probe has been applied for natural water samples, and a satisfied result was obtained.

A Hypochlorite-Activated Theranostic Prodrug for Selective Imaging of High Myeloperoxidase Expression Acute Myeloid Leukemia Cells and Drug Release

“…In recent years, some HClO-responsive fluorescent probes − and theranostic agents , have been developed. Fluorescence imaging has the advantages of perceptual intuition, real-time analysis, low cost, and lack of radiation. − As the overproduction of HClO is involved in many diseases such as cancer and inflammation, new probes that can selectively detect HClO/ClO – in AML cells are required. To facilitate the theranostics of high MPO expression AML, it is necessary to develop targeted fluorescent prodrugs that are activable specifically in these cells.…”

Energy transfer in metal-exchange binuclear complexes covalently linked by asymmetric ligands

“…Transition metal complexes have currently received much interest owing to their unique photophysical properties, such as the MLCT visible absorption and long-lived excited lifetimes, when tuning the ligands with different structural and electronic properties. Ruthenium and osmium complexes played useful roles in catalyses, anticancer activity research, [1][2][3] photoinduced electron or energy transfer, [4][5][6] anion recognizers and fluorescent probes for anion recognizers, [7][8][9] dye-sensitized solar cells, 10,11 and even in the development of bio-inspired oxidation reactions. Ru(II)/Os(II) complexes were also essential for studying the transfer direction and rates of energy and electrons 12 through a π-delocalized bridge induced by light.…”

Selective and Fast‐Response Fluorescent Probes for Hypochlorite and their Application

“…The fluorescent assay is an attractive analytic technique owing to its good selectivity, high sensitivity, and convenience operations . So far, a number of fluorescent probes have been reported for detecting HClO, which exhibited good fluorescent responses and some potential for application.…”