A ratiometric styryl bridging triphenylamine-indolinium based fluorescent dye for detection of cyanide with a large emission shift in human breast cancer cells and test strips

Mandal, Moumi; Karak, Anirban; Halder, Satyajit; Banerjee, Shilpita; Maiti, Anwesha; Jana, Kuladip; Mahapatra, Ajit Kumar; Kar, Arik

doi:10.1080/10610278.2022.2135439

Cited by 5 publications

(2 citation statements)

References 33 publications

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“…After the completion of the incubation period, the media from the well plates containing the cells were removed and washed with 1× PBS, and then they were checked using a DAPI filter under the microscope. 31 It is evident from the MTT analysis that in the presence of the diluted working solution containing 25 μL of PTDP solution, the cells showed the highest viability with the reductions being observed in the case of diluted solutions containing 50 and 75 μL of the PTDP solutions and an undiluted solution of 100 μL of the PTDP solution (Figure S9, Supporting Information).…”

Section: Theoretical Studiesmentioning

confidence: 97%

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A Phenanthrenequinone-Based Ratiometric Fluorescent Probe for Rapid Detection of Peroxynitrite with Imaging in Osteoblast Precursor Cells

Karak,

Banik,

Ganguly

et al. 2024

Chem. Res. Toxicol.

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In the current situation, peroxynitrite (ONOO − ) is drawing the increasing attention of researchers for its pivotal role in diverse pathological and physiological processes on grounds of robust oxidation and nitrification. Herein, we have successfully designed and synthesized a phenanthrenequinone benzyl boratebased chemosensor for fast and selective detection of ONOO − . The probe PTDP itself had an orange fluorescence, which was changed to strong blue fluorescence upon the addition of ONOO − , indicating the ratiometric response of the probe. This is so because of the cleavage of the benzyl boronate-protecting group of PTDP upon the addition of ONOO − with simultaneous releasing of pyridinyl-based chemosensor PPI. The PTDP showed outstanding performance in the various photophysical studies such as good selectivity, excellent sensitivity with a very low detection limit of 2.74 nM, and a very fast response time (<15 s). Furthermore, for practical applicability, it was successfully applied in the ratiometric detection of ONOO − in osteoblast precursor cells.

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Section: Theoretical Studiesmentioning

confidence: 97%

“…For control, the cells were left untreated. After the completion of the incubation period, the media from the well plates containing the cells were removed and washed with 1× PBS, and then they were checked using a DAPI filter under the microscope …”

Section: Applicationmentioning

confidence: 99%