A ratiometric triazine-based colorimetric and fluorometric sensor for the recognition of Zn²⁺ ions and its application in human lung cancer cells

Abstract

Herein, we introduce a new ratiometric 2,4,6-triamino-1,3,5-triazine-based probes (R1 and R2) having three different binding sites for three metal ion binder which can selectively detect Zn2+ ions and particularly the...

A benzothiazole-based dual reaction site fluorescent probe for the selective detection of hydrazine in water and live cells

“…The cells were washed with 1× PBS and then they were mounted on a glass slide and observed under a fluorescence microscope (Olympus) using a DAPI filter. 48 Synthesis of compounds 2-5…”

A dual-channel chemodosimetric sensor for discrimination between hypochlorite and nerve-agent mimic DCP: application on human breast cancer cells

“…Hence, 10 μM was selected as the working concentration of the ligand TPSZ to perform further studies. 36,37…”

“…Hence, 10 μM was selected as the working concentration of the ligand TPSZ to perform further studies. 36,37 Results from fluorescence microscopy imaging showed an increased level of fluorescence intensity at an emission wavelength of 420 nm (blue emission) when the MDA-MB 231 cells were exposed to the ligand TPSZ (10 μM) in combination with OCl − (10 μM) for incubation periods of 15 min and 30 min (Fig. 11(a)).…”

An ICT-guided ratiometric naphthalene–benzothiazole-based probe for the detection of cyanide with real-time applications in human breast cancer cells

“…Briey, the cells were grown in coverslips for 24 h in a 37 C humidied incubator containing 5% CO 2 and then either mock-treated or treated with 10 mM of the ligand MNBTZ in the presence or absence of a 5 mM working concentration of cyanide and incubated for 15 min or 30 min in the dark at 37 C. The cells were then washed with 1Â PBS three times to remove any unbound MNBTZ, then mounted on a glass slide and observed under a uorescence microscope (Olympus) using a DAPI lter. 34,35 Fig. 6…”

“…The cells were then washed with 1× PBS three times to remove any unbound MNBTZ , then mounted on a glass slide and observed under a fluorescence microscope (Olympus) using a DAPI filter. 34,35…”