A Recent 10-Year Clinical and Epidemiological Study on Zoster under 20 Years Old

Mok, Hye Rin; Park, So Young; Lee, Soo Young; Choi, Sang Rhim; Jeong, Dae Chul; Chung, Seung Yun; Kim, Jong Hyun; Hur, Je Kyun; Kang, Jin Han

doi:10.14776/kjpid.2005.12.2.195

Cited by 3 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Furthermore, the incidence of herpes zoster is known to be high in children without immunodeficiency but who have chronic diseases such as asthma or diabetes [252627]. One Korean study reported that the incidence of herpes zoster in children have increased since the mid-1990s, when the varicella vaccine was introduced, and that the median age of incidence is 9.9 years [11].…”

Section: Discussionmentioning

confidence: 99%

“…Although national immunization program (NIP) vaccination, including the varicella vaccine, has been required since 2005 in Korea for children over the age of 1 years, the incidences of varicella and herpes zoster have remained the same. Since the implementation of NIP vaccination, there have been no population-based epidemiological studies on herpes zoster, and systematic epidemiological studies are also lacking [111213], as are comparative studies of herpes zoster in immunocompetent and immunocompromised children. Thus, in this study, we conducted a multi-institutional epidemiological analysis of herpes zoster in children after the introduction of chickenpox vaccination into NIP, as well as a clinical comparative analysis of immunocompetent and immunocompromised children.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A clinico-epidemiological multicenter study of herpes zoster in immunocompetent and immunocompromised hospitalized children

Hwang

Kim

Han

et al. 2019

Clin Exp Vaccine Res

Self Cite

View full text Add to dashboard Cite

Purpose There are limited population-based data regarding herpes zoster in children. Thus we conducted a multi-institutional epidemiological analysis of herpes zoster in children and comparative analysis according to their immune status. Materials and Methods The study included 126 children under the age of 18 years who were hospitalized for herpes zoster at 8 hospitals in South Korea, between July 2009 and June 2015. The subjects were divided into 2 groups according to their immune status, and medical records were reviewed. Results There were 61 cases (48.4%) in the immunocompetent group and 65 cases (51.6%) in the immunocompromised group. Median age was older in immunocompromised group (11.4 vs. 8.6) (p<0.001). The mean duration of hospitalization was longer in immunocompromised group (11.0 vs. 6.6) (p<0.001). Patients were treated with oral or intravenous antiviral agents. A total of 12 in immunocompetent group were cured only by oral acyclovir. No treatment failure was found in both groups. Six immunocompromised patients had postherpetic neuralgia and 1 case was in immunocompetent group. In immunocompetent children, herpes zoster was likely caused by early varicella infection. There was no increase in progression of severity in both groups due to appropriate treatment. Conclusion Early initiation of therapy is necessary for those in immunocompromised conditions. And inactivated herpes zoster vaccination may be considered in immunocompromised adolescents in the future.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A clinico-epidemiological multicenter study of herpes zoster in immunocompetent and immunocompromised hospitalized children

Hwang

Kim

Han

et al. 2019

Clin Exp Vaccine Res

Self Cite

View full text Add to dashboard Cite

show abstract

“…상포진의 의 발병률은 꾸준히 늘어나고 있다 4) . 이같이 12,14) . 소아청소년에서 대상포진이 발생하는 경우는 기저질환이 있는 경우 발병률이 높다고 알려져 있다 [15][16][17] .…”

unclassified

Clinical Features of Herpes Zoster in Children according to Immune Status

Choi¹,

Kim²,

Kwon³

2018

journalofthekoreanchildneurologysociety

View full text Add to dashboard Cite

It is more common in elderly people or immunocompromised people and can be accompanied by serious complications. This study was performed to investigate the clinical manifestation of herpes zoster according to immune status in children. Methods: This study was retrospectively included 307 children under 18 years who were diagnosed and treated with herpes zoster at Inha University Hospital from 1997 to 2017 based on medical records. These patients were divided into two groups according to their immunity and their clinical features were compared. Results: The mean age of the total 307 patients was 10.2 years, 151 (49.2%) in males. Eighty-seven patients were hospitalized and 220 patients were treated in an outpatient clinic. Most patients received antiviral treatment. The most common dermatomal distribution of the skin lesion was the thoracic region, followed by trigeminal, lumbar and sacral, cervical region. Twenty-one patients were immunocompromised and fifteen of them were hematologic disorders. Admission rate, history of chickenpox and mean duration of treatment were significantly higher in immunocompromised group (P<0.05). There was no significant difference in age, dermatomal distribution and complication between the two groups. Complications were observed in 50 cases and more than half of them were zoster ophthalmicus. Another complication was Ramsay-Hunt syndrome, meningitis and skin infection. Conclusion: Immunocompromised patients had a longer duration of treatment and a higher history of chickenpox. The incidence of complications, dermatomal distribution and age did not differ from that of immunocompetent children.

show abstract

Two Cases of Herpes Zoster Following Varicella Vaccination in Immunocompetent Young Children: One Case Caused by Vaccine-Strain

Kim

Kang

Han

et al. 2022

Pediatr Infect Vaccine

View full text Add to dashboard Cite

A Recent 10-Year Clinical and Epidemiological Study on Zoster under 20 Years Old

Cited by 3 publications

References 0 publications

A clinico-epidemiological multicenter study of herpes zoster in immunocompetent and immunocompromised hospitalized children

A clinico-epidemiological multicenter study of herpes zoster in immunocompetent and immunocompromised hospitalized children

Clinical Features of Herpes Zoster in Children according to Immune Status

Two Cases of Herpes Zoster Following Varicella Vaccination in Immunocompetent Young Children: One Case Caused by Vaccine-Strain

Contact Info

Product

Resources

About