In this article, we first review current Japanese urban and regional sociological literature on the COVID-19 pandemic. Some empirical studies of the current conditions, challenges, and difficulties faced by urban communities with the pandemic have loomed large. Although urban governance of infectious disease control has been generally an important research topic in urban studies, there is limited research on this aspect, particularly in Japan. Then, we briefly examine the urban governance of the pandemic in Japan, with a focus on the case of Osaka. Specifically, by analyzing the meeting minutes of Osaka Prefectural Government's countermeasure headquarters, we shed light on what issues were mainly dealt with and what main organizational actors were involved. The results indicate that, in addition to the administrative and political collaboration between central, prefectural, and municipal governments, the involvement of industrial and professional organizations (e.g., medical and economic associations) is particularly salient. This is because the governmental sector in Japan lacks a strong legal framework and a policy implementation capacity for infectious disease control. Consequently, it has requested (through intermediary associations) that residents, businesses, and hospitals cooperate with the government to control the spread of the virus. With regard to the characteristics of the Japanese urban governance of the pandemic, more comparative research between cities and regions in the country and those in other countries will be one of the important issues for future Japanese urban and regional sociology.