A relationship between endoscopic findings and diabetic regulation, and complications in patients with diabetes mellitus

Abstract

IntroductionDiabetes mellitus (DM) is the most common endocrine disease. Increasing with a rapid acceleration, DM affects the society both financially and socially with its possible complications. Dyspeptic complaints occur in approximately 40% of DM patients. Dyspepsia in DM is a difficult condition to treat and requires patients’ frequent hospital visits. We aimed to examine a relationship between diabetic regulation and diabetic complications as well as endoscopic findings in patients with DM and dyspeptic complaints.Material and methodsPatients with a DM diagnosis from internal diseases outpatient clinic of our hospital who were followed-up between January 2019 and June 2020, and who underwent endoscopy for the upper gastrointestinal system were included. Diagnosis of DM was made according to the American Diabetes Association (ADA) criteria. Diabetic complications were questioned. A relationship between endoscopic and histopathological findings, glycated hemoglobin (HbA1c) level, and complications was investigated.ResultsA total of 105 patients, 61 (58%) females, were included into the study. In a comparison between the groups, there was no statistically significant difference between glycemic regulation and endoscopic findings and the presence of HP. Comparing diabetic complications, no significant difference was observed in patients with complications from the endoscopic findings, except for pangastritis. The presence of HP was similar in both groups.ConclusionsIt can be said that endoscopic findings and presence of HP are not closely related to glycemic control and complications in diabetic patients. However, these results should be supported by larger, multi-center, prospective studies.