2024
DOI: 10.22159/ijap.2024v16i2.50059
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A Reliable Rp-Uplc-Tuv Method for Simultaneous Estimation of Clarithromycin, Amoxicillin, and Vonoprazan in Co-Packed Pharmaceutical Dosage Forms: Method Development and Validation With Stability Indicating Properties

K. ANUSHA,
G. SOWJANYA

Abstract: Objective: The study aims to develop a reliable RP-UPLC-TUV method for simultaneous estimation of Clarithromycin, Amoxicillin, and Vonoprazan in bulk and combined dosage. Methods: A simple, specific, and reliable method for determining Clarithromycin, Amoxicillin, and Vonoprazan has been developed using the RP-UPLC method. In order to successfully separate Clarithromycin, Amoxicillin, and Vonoprazan, 1.0 µl of a 100 % level solution was injected into a Hibar C18 (100 x 2.1 mm and 2 µm) column. The mobile phase… Show more

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