A retrospective study of COVID during pregnancy and the outcome of vaginal delivery

Sunuwar, Neela; Jaishi, Prakash Poudel; Twayana, Anu Radha; Neupane, Prabhat Kiran; Neupane, Sandhya Kiran

doi:10.1016/j.amsu.2022.104880

Cited by 3 publications

(3 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, there was no significant difference in neonatal outcomes between the group delivered by vaginal delivery and the group delivered by cesarean section. 18 This correlates with the findings of this systematic review and suggests that DMI proposed early in the pandemic should be specifically reviewed and guidelines for delivery adjusted accordingly.…”

Section: Discussionsupporting

confidence: 85%

“…17 Sunuwar et al described a small retrospective review of 104 women who were SARS-CoV-2-positive during any trimester of pregnancy and delivered by vaginal delivery or cesarean section and followed their neonatal outcomes. 18 They found that in their infants 51% were born with low Apgar scores, 18% were born prematurely, 19% had low birth weight, 7% required neonatal intensive care unit admission, 3% experienced neonatal asphyxia, 2% died, and none were SARS-CoV-2-positive. However, there was no significant difference in neonatal outcomes between the group delivered by vaginal delivery and the group delivered by cesarean section.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Optimal Delivery Management for the Prevention of Early Neonatal SARS-CoV-2 Infection: Systematic Review and Meta-analysis

Chan,

Kong,

Sultana

et al. 2024

Am J Perinatol

View full text Add to dashboard Cite

Objective: Delivery management interventions (DMI) were recommended to prevent delivery-associated transmission of maternal SARS-CoV-2 to infants without evidence of effect on early neonatal SARS-CoV-2 infection (ENI) and neonatal death <28 days of life (ND). This systematic review describes different DMI combinations and the frequency of ENI and ND. Study Design: Individual patient data were collected from articles published 1 January 2020 - 31 December 2021 from Cochrane review databases, Medline and Google Scholar. Article inclusion criteria were: Documented maternal SARS-CoV-2 PCR positive status 10 days before delivery or symptomatic at delivery with a positive test within 48 hours, known delivery method and known infant SARS-CoV-2 PCR result. Primary outcomes were ENI (positive PCR at 12 hours-10 days) and ND. All characteristics were pooled using DerSimonian-Laird inverse variance method. Primary outcome analyses were carried out using logit transformation and random effect. Pooled results were expressed as percentages (95% confidence intervals). Continuity correction was applied for all pooled results if any included study has 0 event. Results: 11,075 publications were screened. 117 publications representing 244 infants and 230 mothers were included. All publications were case reports. ENI and ND were reported in 23.4% (18.2, 29.18) and 2.1% (0.67, 4.72) of cases respectively. Among cases with available information, DMIs were reported for physical environment (85-100%), delivery specific interventions (47-100%), and infant care practices (80-100%). No significant comparisons could be performed between different DMI combinations due to small sample size. Conclusion: The evidence supporting any DMI in SARS-CoV-2 infected mothers to prevent ENI nor ND is extremely limited. Limitations of this meta-analysis include high risk of bias, small sample size and large confidence intervals. This identifies the need for multinational database generation and specific studies designed to provide evidence of DMI guidelines best suited to prevent transmission from mother to neonate.

show abstract

Section: Discussionsupporting

confidence: 85%

Section: Discussionmentioning

confidence: 99%

Optimal Delivery Management for the Prevention of Early Neonatal SARS-CoV-2 Infection: Systematic Review and Meta-analysis

Chan,

Kong,

Sultana

et al. 2024

Am J Perinatol

View full text Add to dashboard Cite

show abstract

“…There were no miscarriages or congenital anomalies in our study population. Other studies from Nepal during the pandemic time also had similar findings 15 .…”

Section: Discussionsupporting

confidence: 63%

Assessment of severity and feto-maternal outcomes among COVID-19 infected pregnant females hospitalized at tertiary care center in western Nepal

Pandit,

Paneru,

Chapagain

et al. 2024

Annals of Medicine &Amp; Surgery

View full text Add to dashboard Cite

Objective: There is a paucity of data assessing the severity of COVID-19 infection and feto-maternal outcomes in pregnant women in Nepal, especially during the third wave of the pandemic with the Delta variant. This study aimed to severity as well as maternal-fetal outcomes among pregnant women with COVID-19 infection. Methods: In this cross-sectional study carried out amongst COVID-19-positive pregnant women visiting our institution for six months from January through June 2022, data surrounding COVID-19 severity and fetal outcomes were collected in a structured questionnaire. Disease severity was categorized based on the NIH (National Institutes of Health) severity classification. Descriptive statistics were used to describe the outcomes. Results: A total of 105 pregnant females infected with COVID-19 during the third wave were included in our study. The participants ranged from 16 through 40 years, mean gestational age being 36.6 weeks. Most of the women (40.55%) belonged to Brahmin and Chhetri ethnic backgrounds. About half (48.55%) of females were asymptomatic and four patients had severe disease requiring intensive care management. Only 13 pregnant females underwent vaccination. Of the 91 females that underwent delivery at our center, 77 (84.62%) were term. The rate of cesarean delivery was slightly higher (51.65%) than normal delivery. None of the babies born to COVID-positive pregnant females tested positive for COVID-19 and there were no stillbirths or any congenital anomalies. The majority of babies (68.14%) had normal fetal weight. Conclusion: Severe COVID-19 infection and adverse maternal-fetal outcomes during the third wave of COVID-19 infection with the Delta variant in Nepal were less than in other regions of the world despite low rates of vaccination.

show abstract

Investigating the mode of transmission of COVID-19 through genital secretions, semen, the birth canal, and lactation: A systematic review

Meamar,

Farajkhoda,

Afshani

et al. 2024

Journal of Education and Health Promotion

View full text Add to dashboard Cite

In a global pandemic, the coronavirus has brought new challenges to reproductive and sexual health. This systematic review has been conducted with the aim of investigating a) the transmission of coronavirus disease 2019 (COVID-19) through female-to-male sexual secretions and vice versa, b) vertical transmission to the fetus, c) transmission to the newborn through the birth canal, and d) transmission through breast milk. In this review study, to find related articles, databases were searched using English and Persian keywords from the beginning of 2019 to the end of 2023. Based on the entry and exit criteria and the qualitative evaluation of the studies based on the STROBE criterion, the final studies were summarized. According to the initial search, 5970 articles were reviewed. After removing duplicate articles and the inappropriateness of the title, the abstract of the article was not related to the objectives of the project, there was no relevant study, and retrospective studies were excluded. Finally, 120 articles were selected as final articles. The general results show that transmission of the virus through the vagina to the blood of the fetus causing septicemia, vertical transmission from the mother to the fetus, transmission through the water bag, genital secretions, and ejaculate fluid are considered rare and ruled out. Transmission through rectal secretions during anal or oral sex requires more extensive studies. It is not possible to transmit the virus through breast milk. The long-term reproductive impact of COVID-19 on the reproductive systems of women and men is unclear.

show abstract

A retrospective study of COVID during pregnancy and the outcome of vaginal delivery

Cited by 3 publications

References 20 publications

Optimal Delivery Management for the Prevention of Early Neonatal SARS-CoV-2 Infection: Systematic Review and Meta-analysis

Optimal Delivery Management for the Prevention of Early Neonatal SARS-CoV-2 Infection: Systematic Review and Meta-analysis

Assessment of severity and feto-maternal outcomes among COVID-19 infected pregnant females hospitalized at tertiary care center in western Nepal

Investigating the mode of transmission of COVID-19 through genital secretions, semen, the birth canal, and lactation: A systematic review

Contact Info

Product

Resources

About