A retrospective study on T3N0 laryngeal cancer

Abstract

This study was conducted to evaluate the clinical outcomes of 53 patients with T3N0M0 larynx squamous cell carcinoma in our hospital between May 2006 and March 2019. The subjects were 48 men and 5 women, ranging in age from 47 to 88 years, with mean age of 72 years. The treatment was surgery in 26 patients, chemoradiotherapy (CRT) in 17 patients, and radiotherapy alone (RT) in 10 patients. The 3-year overall survival (OS) rate was 79.2％, and the 3-year disease-specific survival (DSS) rate was 84.4％.The total 3-year larynx preservation rate was 37.3％, 48％ for RT cases, and 81.6％ for CRT cases.Treatment with chemoradiotherapy improved larynx preservation rate versus radiotherapy alone (p＜ 0.05) . The 3-year OS rate was 82.2％ for surgery cases, 94.1％ for CRT cases, and 48％ for RT cases. Our therapeutic approach of using surgery or CRT showed successful outcomes for OS and DSS.