“…Several SRs and meta-analyses which evaluated the comparative effects of EIN versus standard EN have been published. 8 , 25 , 26 , 46 – 48 In addition, of these six SRs, two systematically assessed the direct evidences between preoperative or postoperative versus perioperative EIN methods. 8 , 26 However, it is noted that these SRs and meta-analyses were performed by using traditional pair-wise meta-analysis method which cannot compare >2 treatments concerning certain topic simultaneously.…”