A review on classical Vajikarana formulations of Shweta Musali

Khan, Mujahid; Rathi, Bharat; Rajput, Dhirajsingh; Wanjari, Anita

doi:10.4103/jism.jism_67_19

Cited by 5 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Regular vigorous dynamic conjugation with average quantitative semen in Ashwa (Horse) (101). (102). Shathavari Ghritha when consumed along with milk and licorice powder is an excellent aphrodisiac (103).…”

Section: Licorice As Aphrodisiac (Vrisya)mentioning

confidence: 99%

Ethnopharmacological study about Glycyrrhiza glabra L. (Licorice) based on Ayurveda, An Indian System of Traditional Medicine- A Review

Chandran¹,

Syam²,

Jerone³

et al. 2022

IJAM

View full text Add to dashboard Cite

Glycyrrhiza glabra L. (GG), also known as Yashtimadhu, is a traditional plant which is widely used in Ayurveda. It is used to treat a variety of ailments including cough, asthma, bronchitis, diabetes, gastric ulcers, skin problems, inflammation, anaemia, premature greying of hair and others. Clinical and experimental research suggests that it possesses anti-inflammatory, antiviral, immunomodulatory, hepatoprotective, antimicrobial, antioxidant, anticancer, and cardioprotective activities. We gathered material on the phytochemistry, pharmacology, and toxicity of Glycyrrhiza glabra published before March 2022 from PubMed, Springer, SCOPUS, Google Scholar and Science Direct. To compile this study, we conducted a thorough analysis of the classical Ayurvedic treatises in order to obtain a full account of the qualities, actions, and applications stated in Ayurveda about yashtimadhu in order to demonstrate ancient-modern concordance. GG has been studied for a variety of pharmacological properties, including ulcer healing, anti-ulcerogenic, anti-bacterial, antioxidant potential activity, anti-asthmatic activity, hair growth stimulating activity, and memory enhancing action. Licorice in Ayurveda is generally used in Ayurveda as a rejuvenator and aphrodisiac, as well as for boosting memory, complexion, sound quality, dental health, vision, lactation, and healing cancer, ulcers and wounds. Even though GG is a widely used Ayurveda medicine, there is a lack of evidence regarding the true medicinal potential of the drug. There are innumerable actions mentioned in the Ayurveda classical textbooks. Here, an effort is made to find substantiation for the ancient wisdom through a thorough search with the modern available literature.

show abstract

Section: Licorice As Aphrodisiac (Vrisya)mentioning

confidence: 99%

Ethnopharmacological study about Glycyrrhiza glabra L. (Licorice) based on Ayurveda, An Indian System of Traditional Medicine- A Review

Chandran¹,

Syam²,

Jerone³

et al. 2022

IJAM

View full text Add to dashboard Cite

show abstract

“…Plant origin drugs have been used since the beginning of civilization to sustain health and treat disease (Khan et al, 2019). Tinospora cordifolia is native to lower elevation in tropical areas of the Indian subcontinent and it is broadly spreading glabrous, a perennial deciduous climbing shrub which climbs numerous types of trees.…”

Section: Importance Of Tinospora Cordifolia In Traditional Indian Systemmentioning

confidence: 99%

Tinospora Cordifolia-An immunomodulatory drug in Ayurveda for prevention and treatment of Covid-19

Khan

Rathi

2020

ijrps

View full text Add to dashboard Cite

‘COVID-19’ is a highly infectious disease caused by the virus SARS-CoV-2 and it becomes a global pandemic in a very short period. Currently, there is a lack of precise management or vaccine available to counteract this disease which mainly attacks the immune system of a body. To manage COVID-19 existing disease-modifying and anti-virals agents and are being repurposed. Many research types are conducted in the development of particular immunomodulators, anti-virals agent or vaccines for SARS-CoV-2. In Ayurveda concept of epidemic condition (Janapadodhwanasa) is explained and various measures mentioned for prevention and treatment against such conditions including Rasayan dravyas (immunomodulator drugs). Tinospora cordifolia (Willd.) Miers is one of an immune-modulator drug in Ayurveda which known to possess properties like antioxidant, immunomodulatory, anti-inflammatory, anti- antiallergic, antiviral hyperglycaemic etc. This herb chiefly contains compounds like glycosides, alkaloids, steroids, diterpenoid lactones, sesquiterpenoid, aliphatic compound. Scientific researches on this drug may provide a new approach as well as insight for prevention, management and development of new therapeutic entity to treat COVID-19. The current review focus on researches conducted on properties of Tinospora cordifolia in the view of possible application in the prevention and treatment of COVID-19.

show abstract

“…It was suggested that this formulation be taken orally with a vehicle such as cows' ghee or cows' milk. (7) This herbal combination could be beneficial, but chemical concoctions can be detrimental and genotoxic, causing damage to the genetic material of living cells and leading in mutations that create major issues for the host, such as cancer and birth defects; therefore, genotoxicity testing is essential. However, research on some of the ingredients in Musalyadi Churna has shown that they have antioxidant, immunomodulator, anticancer and genoprotective properties.…”

Section: Introductionmentioning

confidence: 99%

Genotoxic, antigenotoxic and protective evaluation of Musalyadi churna by chromosomal aberration assay in Swiss albino mice

Khan¹,

Rathi²,

Rathi³

et al. 2022

IJAM

View full text Add to dashboard Cite

Ayurveda is an ancient science of life that uses a wide range of formulations or herbal compounds to treat various diseases. Each drug must be scientifically, pre-clinically, and clinically evaluated in order to gain global acceptance. As part of the safety evaluation process, regulatory authorities around the world require data on new drug genotoxic potential.MusalyadiChurna(MSDC) is a classical Ayurvedic formulation in herbal powder dosage form consisting of eight ingredients of herbal origin and indicatedin the treatment infertility. This herbal combination may be useful, however mixture of substances can be dangerous and genotoxic, causing harm to living cells' genetic material and resulting in mutations that induce serious issues for the host, such as cancer and birth defects; consequently, genotoxicity testing is essential.The study aimed to evaluate the genotoxic, antigenotoxic and protective properties of MusalyadiChurnaagainst the bone marrow of albino mice. MusalyadiChurna's genotoxicity were assessed using the "Mammalian Bone Marrow Chromosome Aberration assay," and the classical powder's antigenotoxic and protective activities against cyclophosphamide-induced genotoxicity in mice were also assessed using the same assay.Mice were administered MusalyadiChurna orally for four weeks at a dose of 25 mg/25 g mouse. Cyclophosphamide was utilized as a mutagen, and a single dose of 50 mg/kg b.w. was given intraperitoneally (i.p.) 24 hours after the final dose of MusalyadiChurna in the pre-treatment regimen and 24 hours before the first dose of MusalyadiChurna in the post-treatment regimen.The chromosomal aberration assay revealed that the herbal compound formulation MusalyadiChurnaat 1000 mg/Kg body wt. had no genotoxic activity against the bone marrow of Swiss albino mice. Using the same experiment, the formulation demonstrated both protective and antigenotoxic properties against Cyclophosphamide-induced mutagenicity in mice.Further research should be to capitalize on MusalyadiChurna’s potential as an alternative source of natural compounds to treat genotoxic problems.

show abstract

A review on classical Vajikarana formulations of Shweta Musali

Cited by 5 publications

References 0 publications

Ethnopharmacological study about Glycyrrhiza glabra L. (Licorice) based on Ayurveda, An Indian System of Traditional Medicine- A Review

Ethnopharmacological study about Glycyrrhiza glabra L. (Licorice) based on Ayurveda, An Indian System of Traditional Medicine- A Review

Tinospora Cordifolia-An immunomodulatory drug in Ayurveda for prevention and treatment of Covid-19

Genotoxic, antigenotoxic and protective evaluation of Musalyadi churna by chromosomal aberration assay in Swiss albino mice

Contact Info

Product

Resources

About