A Review on Extraction of Lipase from Aspergillus Species and its Applications

Abstract

Lipase enzyme which catalyses the hydrolysis of fats performs a variety of chemical reactions including esterification, trans-esterification, acidolysis and aminolysis. Lipases are widely used for biotechnological application in dairy industry, oil processing and production of surfactants and preparation of enatiomerically pure pharmaceuticals. Lipases are extracted from plants, animals and microorganisms whereas high amount of lipases are produced by microbes when compared to plants and animal source. Fungi serve as a major source in the production of industrial lipase. Fungi play a vital role in removing hazardous compounds formed by crude oil contamination from oil spill during lipase extraction. Aspergillus flavus, Aspergillus niger, Penicillium restrictum, Rhizomucar rhizopodiformis, Rhizopus oligosporous, Candida rugosa, Rhizopus oryzae, Fusarium oxysporum are few fungal species involved in the production of lipase. Among the species, Aspergillus species produce efficient amount of lipase. Lipase extracted from fungi is more stable and have more diverse properties compared to lipase from other source. Fungal lipases stand out as major source because of their catalytic activity, low cost of production and relative ease in genetic manipulation. This review focuses on the various methods of lipase extraction from Aspergillus species and its applications.

Evaluation and Characterization of Lipase Production in Aspergillus niger Isolate Qurna for Biotechnological Applications

“…Lipases, enzymes instrumental in fat breakdown and facilitators of various chemical reactions, including esterification, trans-esterification, acidolysis, and aminolysis, have emerged as pivotal biocatalysts in diverse industrial sectors. Their applications span multiple sectors such as the dairy industry, oil processing, surfactant production, and the synthesis of enantiomerically pure pharmaceuticals [1]. Despite their presence in plants, animals, and microorganisms, fungi have been identified as the primary and most prolific source of industrially relevant lipases.…”

“…Despite their presence in plants, animals, and microorganisms, fungi have been identified as the primary and most prolific source of industrially relevant lipases. They play a vital role in the remediation of hazardous compounds generated during lipase extraction, particularly in scenarios like oil spills caused by crude oil contamination [1].…”

“…Fungal isolates, a key component of biotechnology, are crucial in unlocking the potential of microorganisms for a variety of industrial uses. Among the numerous enzymes produced by fungi, lipases have drawn significant interest due to their myriad uses in various industries, including dairy, oil processing, surfactant creation, and the synthesis of enantiomerically pure pharmaceuticals [1].…”