A REVIEW ON THE APPLICATION OF CRISPR/Cas9-GENOME EDITING TOOL

Abstract

CRISPR-CAS9, a bacterial defensive genome editing mechanism against phages, introduced by Jennifer Doudna and Emmanuelle Charpentier as a system that can be programmed and reprogrammed in 2012, is a modern revolutionary bioscience tool with applications far beyond the present-day scientic boundaries. With its accelerating advancements in elds ranging from agriculture, horticulture, genetic disorders, biomedicines, live-imaging of genes, epigenetic editing, CRISPR technology has already altered the biological perspective in a great deal. In this review paper, an overview of the CRISPR/CAS9 technology and its applications in agricultural and bio-medicinal eld of studies based on previously available works of literature, has been shortly summarized.