2022
DOI: 10.2478/aoas-2022-0089
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A review on the epigenetics modifications to nanomaterials in humans and animals: novel epigenetic regulator

Abstract: In the nanotechnology era, nanotechnology applications have been intensifying their prospects to embrace all the vigorous sectors persuading human health and animal. The safety and concerns regarding the widespread use of engineered nanomaterials (NMA) and their potential effect on human health still require further clarification. Literature elucidated that NMA exhibited significant adverse effects on various molecular and cellular alterations. Epigenetics is a complex process resulting in the interactions bet… Show more

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“…The genome contains the two categories of genetic evidence and epigenetic evidence provided by DNA sequences. The epigenetic exhibits the relationship of epigenetic alterations with the regulation of gene expression and differentiation, as well as genomic modifications in gene activity, without changing the DNA sequence [95,96]. The genome of mitochondria shortens the safeguard of histones and multifarious DNA repair machinery [97,98] due to its vulnerable to OS, resulting in fluctuations in mtDNA mutation.…”
Section: Genetic and Epigenetic Modifications In Admentioning
confidence: 99%
“…The genome contains the two categories of genetic evidence and epigenetic evidence provided by DNA sequences. The epigenetic exhibits the relationship of epigenetic alterations with the regulation of gene expression and differentiation, as well as genomic modifications in gene activity, without changing the DNA sequence [95,96]. The genome of mitochondria shortens the safeguard of histones and multifarious DNA repair machinery [97,98] due to its vulnerable to OS, resulting in fluctuations in mtDNA mutation.…”
Section: Genetic and Epigenetic Modifications In Admentioning
confidence: 99%